Difference between revisions of "Colorectal xanthomatous polyp"
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*Rare.<ref name=pmid12009096>{{Cite journal | last1 = Miliauskas | first1 = JR. | title = Rectosigmoid (colonic) xanthoma: a report of four cases and review of the literature. | journal = Pathology | volume = 34 | issue = 2 | pages = 144-7 | month = Apr | year = 2002 | doi = | PMID = 12009096 }}</ref> | *Rare.<ref name=pmid12009096>{{Cite journal | last1 = Miliauskas | first1 = JR. | title = Rectosigmoid (colonic) xanthoma: a report of four cases and review of the literature. | journal = Pathology | volume = 34 | issue = 2 | pages = 144-7 | month = Apr | year = 2002 | doi = | PMID = 12009096 }}</ref> | ||
*May be associated with hyperlipidemia (7/25 patients in one series<ref name=pmid14961968>{{Cite journal | last1 = Nakasono | first1 = M. | last2 = Hirokawa | first2 = M. | last3 = Muguruma | first3 = N. | last4 = Okahisa | first4 = T. | last5 = Okamura | first5 = S. | last6 = Ito | first6 = S. | last7 = Miyamoto | first7 = H. | last8 = Wada | first8 = S. | last9 = Fukuda | first9 = T. | title = Colorectal xanthomas with polypoid lesion: report of 25 cases. | journal = APMIS | volume = 112 | issue = 1 | pages = 3-10 | month = Jan | year = 2004 | doi = | PMID = 14961968 }}</ref>). | *May be associated with hyperlipidemia (7/25 patients in one series<ref name=pmid14961968>{{Cite journal | last1 = Nakasono | first1 = M. | last2 = Hirokawa | first2 = M. | last3 = Muguruma | first3 = N. | last4 = Okahisa | first4 = T. | last5 = Okamura | first5 = S. | last6 = Ito | first6 = S. | last7 = Miyamoto | first7 = H. | last8 = Wada | first8 = S. | last9 = Fukuda | first9 = T. | title = Colorectal xanthomas with polypoid lesion: report of 25 cases. | journal = APMIS | volume = 112 | issue = 1 | pages = 3-10 | month = Jan | year = 2004 | doi = | PMID = 14961968 }}</ref>). | ||
==Gross== | |||
*Yellow or cream colour.<ref name=pmid12009096/> | |||
==Microscopic== | ==Microscopic== | ||
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*[[Hyperplastic polyp of the colon|Hyperplastic polyp]]. | *[[Hyperplastic polyp of the colon|Hyperplastic polyp]]. | ||
*[[Signet ring cell carcinoma]]. | *[[Signet ring cell carcinoma]]. | ||
==IHC== | |||
*CD68 +ve (foamy histiocytes).<ref name=pmid12009096/> | |||
==Sign out== | ==Sign out== | ||
Revision as of 13:22, 20 March 2014
The colorectal xanthomatous polyp, also colorectal xanthoma, is a rare benign intestinal polyp.
General
Gross
- Yellow or cream colour.[1]
Microscopic
Features:
- Abundant foamy histiocytes in the superficial lamina propria.
- +/-Superficial serrations (hyperplastic features).
- Seen in ~80% of cases.[2]
DDx:
IHC
- CD68 +ve (foamy histiocytes).[1]
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POLYP, SIGMOID COLON, POLYPECTOMY: - XANTHOMATOUS POLYP WITH HYPERPLASTIC FEATURES. - NEGATIVE FOR DYSPLASIA. COMMENT: Xanthomatous polyps may be seen in the context of hyperlipidemia.
See also
References
- ↑ 1.0 1.1 1.2 Miliauskas, JR. (Apr 2002). "Rectosigmoid (colonic) xanthoma: a report of four cases and review of the literature.". Pathology 34 (2): 144-7. PMID 12009096.
- ↑ 2.0 2.1 Nakasono, M.; Hirokawa, M.; Muguruma, N.; Okahisa, T.; Okamura, S.; Ito, S.; Miyamoto, H.; Wada, S. et al. (Jan 2004). "Colorectal xanthomas with polypoid lesion: report of 25 cases.". APMIS 112 (1): 3-10. PMID 14961968.