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The '''colorectal xanthomatous polyp''' | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = Xanthomatous polyp -- intermed mag.jpg | |||
| Width = | |||
| Caption = Colorectal xanthomatous polyp. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = abundant foamy histiocytes in the superficial lamina propria +/- superficial serrations (hyperplastic features) | |||
| Subtypes = | |||
| LMDDx = [[hyperplastic polyp]], [[signet ring cell carcinoma]], others | |||
| Stains = | |||
| IHC = CD68 +ve, pankeratin -ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[colon]], [[rectum]] | |||
| Assdx = +/-hyperlipidemia | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = polyp - red or yellow colour | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = other [[colorectal polyps]] | |||
| Tx = | |||
}} | |||
The '''colorectal xanthomatous polyp''', also '''colorectal xanthoma''', is a rare benign [[intestinal polyp]]. | |||
'''Rectal xanthoma''', '''colonic xanthoma''', '''rectal xanthelasma''' and '''colonic xanthelasma''' redirect here. | '''Rectal xanthoma''', '''colonic xanthoma''', '''rectal xanthelasma''' and '''colonic xanthelasma''' redirect here. | ||
''Colorectal xanthomatous polyp'' may be abbreviated '''CXP'''. | |||
==General== | ==General== | ||
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*[[Hyperplastic polyp of the colon|Hyperplastic polyp]]. | *[[Hyperplastic polyp of the colon|Hyperplastic polyp]]. | ||
*[[Signet ring cell carcinoma]]. | *[[Signet ring cell carcinoma]]. | ||
*[[Whipple disease]]. | *[[Whipple disease]]. | ||
*[[Mycobacterium avium complex]]. | *[[Mycobacterium avium complex]]. | ||
===Images=== | |||
<gallery> | |||
Image: Xanthomatous polyp -- very low mag.jpg | XP - very low mag. | |||
Image: Xanthomatous polyp -- low mag.jpg | XP - low mag. | |||
Image: Xanthomatous polyp -- intermed mag.jpg | XP - intermed. mag. | |||
Image: Xanthomatous polyp - alt -- intermed mag.jpg | XP - intermed. mag. | |||
Image: Xanthomatous polyp -- high mag.jpg | XP - high mag. | |||
Image: Xanthomatous polyp -- very high mag.jpg | XP - very high mag. | |||
Image: Xanthomatous polyp - a2 -- very high mag.jpg | XP - very high mag. | |||
</gallery> | |||
==Stains== | |||
*[[ZN stain]] -ve. | |||
*[[PAS stain]] -ve. | |||
==IHC== | ==IHC== | ||
*CD68 +ve (foamy histiocytes).<ref name=pmid12009096/> | *CD68 +ve (foamy histiocytes).<ref name=pmid12009096/> | ||
*Pankeratin -ve. | |||
==Sign out== | ==Sign out== | ||
<pre> | |||
Polyp, Rectum, Polypectomy or Biopsy: | |||
- Xanthomatous polyp with hyperplastic features, see comment. | |||
- NEGATIVE for dysplasia. | |||
COMMENT: | |||
Xanthomatous polyps may be seen in the context of hyperlipidemia.[1] A lipid | |||
profile could be considered. | |||
1. APMIS 112 (1): 3-10. PMID: 14961968. | |||
</pre> | |||
===Block letters=== | |||
<pre> | <pre> | ||
POLYP, SIGMOID COLON, POLYPECTOMY: | POLYP, SIGMOID COLON, POLYPECTOMY: | ||
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*[[Intestinal polyps]]. | *[[Intestinal polyps]]. | ||
*[[Gastric xanthoma]]. | *[[Gastric xanthoma]]. | ||
*[[Urinary bladder xanthoma]]. | |||
==References== | ==References== |
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