48,436
edits
Difference between revisions of "Colorectal xanthomatous polyp"
Jump to navigation
Jump to search
Colorectal xanthomatous polyp (view source)
Revision as of 16:24, 22 July 2015
, 16:24, 22 July 2015→See also
(+synonyms) |
|||
| (8 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Xanthomatous polyp -- intermed mag.jpg | |||
| Width = | |||
| Caption = Colorectal xanthomatous polyp. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = abundant foamy histiocytes in the superficial lamina propria +/- superficial serrations (hyperplastic features) | |||
| Subtypes = | |||
| LMDDx = [[hyperplastic polyp]], [[signet ring cell carcinoma]], others | |||
| Stains = | |||
| IHC = CD68 +ve, pankeratin -ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[colon]], [[rectum]] | |||
| Assdx = +/-hyperlipidemia | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = polyp - red or yellow colour | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = other [[colorectal polyps]] | |||
| Tx = | |||
}} | |||
The '''colorectal xanthomatous polyp''', also '''colorectal xanthoma''', is a rare benign [[intestinal polyp]]. | The '''colorectal xanthomatous polyp''', also '''colorectal xanthoma''', is a rare benign [[intestinal polyp]]. | ||
'''Rectal xanthoma''', '''colonic xanthoma''', '''rectal xanthelasma''' and '''colonic xanthelasma''' redirect here. | '''Rectal xanthoma''', '''colonic xanthoma''', '''rectal xanthelasma''' and '''colonic xanthelasma''' redirect here. | ||
''Colorectal xanthomatous polyp'' may be abbreviated '''CXP'''. | |||
==General== | ==General== | ||
| Line 8: | Line 41: | ||
==Gross== | ==Gross== | ||
* | *Usually red colour.<ref name=pmid14961968/> | ||
**Classically described as ''yellow''.<ref name=pmid12009096/><ref name=pmid14961968/> | |||
==Microscopic== | ==Microscopic== | ||
| Line 19: | Line 53: | ||
*[[Hyperplastic polyp of the colon|Hyperplastic polyp]]. | *[[Hyperplastic polyp of the colon|Hyperplastic polyp]]. | ||
*[[Signet ring cell carcinoma]]. | *[[Signet ring cell carcinoma]]. | ||
*[[Whipple disease]]. | |||
*[[Mycobacterium avium complex]]. | |||
===Images=== | |||
<gallery> | |||
Image: Xanthomatous polyp -- very low mag.jpg | XP - very low mag. | |||
Image: Xanthomatous polyp -- low mag.jpg | XP - low mag. | |||
Image: Xanthomatous polyp -- intermed mag.jpg | XP - intermed. mag. | |||
Image: Xanthomatous polyp - alt -- intermed mag.jpg | XP - intermed. mag. | |||
Image: Xanthomatous polyp -- high mag.jpg | XP - high mag. | |||
Image: Xanthomatous polyp -- very high mag.jpg | XP - very high mag. | |||
Image: Xanthomatous polyp - a2 -- very high mag.jpg | XP - very high mag. | |||
</gallery> | |||
==Stains== | |||
*[[ZN stain]] -ve. | |||
*[[PAS stain]] -ve. | |||
==IHC== | ==IHC== | ||
*CD68 +ve (foamy histiocytes).<ref name=pmid12009096/> | *CD68 +ve (foamy histiocytes).<ref name=pmid12009096/> | ||
*Pankeratin -ve. | |||
==Sign out== | ==Sign out== | ||
| Line 30: | Line 82: | ||
COMMENT: | COMMENT: | ||
Xanthomatous polyps may be seen in the context of hyperlipidemia. | Xanthomatous polyps may be seen in the context of hyperlipidemia.[1] A lipid | ||
profile could be considered. | |||
1. APMIS 112 (1): 3-10. PMID: 14961968. | |||
</pre> | </pre> | ||
| Line 36: | Line 91: | ||
*[[Intestinal polyps]]. | *[[Intestinal polyps]]. | ||
*[[Gastric xanthoma]]. | *[[Gastric xanthoma]]. | ||
*[[Urinary bladder xanthoma]]. | |||
==References== | ==References== | ||