Difference between revisions of "Colon"

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[[Image:Blausen_0603_LargeIntestine_Anatomy.png|thumb|right|Anatomy of the colon and rectum. (WC)]]  
[[Image:Blausen_0603_LargeIntestine_Anatomy.png|thumb|right|Anatomy of the colon and rectum. (WC)]]
The '''colon''' is section of the large bowel.  This article also covers the '''rectum''' and '''cecum''' as both have a similar mucosa.   
The '''colon''' is section of the large bowel.  This article also covers the '''rectum''' and '''cecum''' as both have a similar mucosa.   


It commonly comes to pathologists because there is a suspicion of [[colorectal cancer]] or a known history of [[inflammatory bowel disease]] (IBD).  
It commonly comes to pathologists because there is a suspicion of [[colorectal cancer]] or a known history of [[inflammatory bowel disease]] (IBD).


An introduction to gastrointestinal pathology is found in the ''[[gastrointestinal pathology]]'' article.  The ''[[anus]]'' and ''[[ileocecal valve]]'' are dealt with in separate articles.
An introduction to gastrointestinal pathology is found in the ''[[gastrointestinal pathology]]'' article.  The ''[[anus]]'' and ''[[ileocecal valve]]'' are dealt with in separate articles.


Technically, the rectum and cecum are ''not'' part of the colon.  Thus, inflammation of the rectum should be ''proctitis'' and inflammation of the cecum should be ''cecitis''.
Technically, the rectum and cecum are ''not'' part of the colon.  Thus, inflammation of the rectum should be ''proctitis'' and inflammation of the cecum should be ''cecitis''.
=Anatomy=
*The [[rectum]] has several definition. These are discussed in the ''[[rectum]]'' article.
*The large bowel may be submitted with segment names or with the distance to the anal verge.
A conversion between named segments and distance - as per NCI of the United States:<ref>URL: [https://training.seer.cancer.gov/colorectal/anatomy/figure/figure1.html]https://training.seer.cancer.gov/colorectal/anatomy/figure/figure1.html]. Accessed on: 8 February 2018.</ref>
{| class="wikitable sortable"
!Named segment
!Distance to anal verge (cm)
|-
|Anus
|0-4
|-
|[[Rectum]]
|4-16
|-
|Rectosigmoid
|15-17
|-
|Sigmoid
|17-57
|-
|Descending
|57-82
|-
|Transverse
|82-132
|-
|Ascending
|132-147
|-
|Cecum
|150
|}


=Common clinical problems=
=Common clinical problems=
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# Subtotal colectomy - part of colon removed --or-- some of the rectum remains.
# Subtotal colectomy - part of colon removed --or-- some of the rectum remains.
# Right hemicolectomy - right colon + distal ileum.
# Right hemicolectomy - right colon + distal ileum.
# Lower anterior resection (LAR) - proximal rectum +/- sigmoid (for proximal rectal malignancies).
# [[Lower anterior resection]] (LAR) - proximal rectum +/- sigmoid (for proximal rectal malignancies).
#* Specimens have should have intact mesorectum - ''[[total mesorectal excision]]'' (TME) - reduces local recurrence.<ref name=pmid8665198>{{Cite journal  | last1 = Arbman | first1 = G. | last2 = Nilsson | first2 = E. | last3 = Hallböök | first3 = O. | last4 = Sjödahl | first4 = R. | title = Local recurrence following total mesorectal excision for rectal cancer. | journal = Br J Surg | volume = 83 | issue = 3 | pages = 375-9 | month = Mar | year = 1996 | doi =  | PMID = 8665198 }}</ref>  
#* Specimens have should have intact mesorectum - ''[[total mesorectal excision]]'' (TME) - reduces local recurrence.<ref name=pmid8665198>{{Cite journal  | last1 = Arbman | first1 = G. | last2 = Nilsson | first2 = E. | last3 = Hallböök | first3 = O. | last4 = Sjödahl | first4 = R. | title = Local recurrence following total mesorectal excision for rectal cancer. | journal = Br J Surg | volume = 83 | issue = 3 | pages = 375-9 | month = Mar | year = 1996 | doi =  | PMID = 8665198 }}</ref>  
# Abdominoperineal resection (APR) - anus + rectum - results in a permanent [[stoma]] (for distal rectal malignancies).
# [[Abdominoperineal resection]] (APR) - anus + rectum - results in a permanent [[stoma]] (for distal rectal malignancies).
# [[Stoma]] - these are often done emergently and then get cut-out after the patient's condition has settled.
# [[Stoma]] - these are often done emergently and then get cut-out after the patient's condition has settled.
#[[Doughnuts]] (also ''donuts'') from an end-to-end anastomosis stapler.
#[[Doughnuts]] (also ''donuts'') from an end-to-end anastomosis stapler.
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**Rectum starts/sigmoid ends @ place where serosa ends on the posterior aspect of the bowel.
**Rectum starts/sigmoid ends @ place where serosa ends on the posterior aspect of the bowel.
***The proximal, anterior aspect of the rectum has serosa, i.e. it is not painted.
***The proximal, anterior aspect of the rectum has serosa, i.e. it is not painted.
Note:
*There are several definitions for the rectum.<ref name=pmid24130630>{{Cite journal  | last1 = Kenig | first1 = J. | last2 = Richter | first2 = P. | title = Definition of the rectum and level of the peritoneal reflection - still a matter of debate? | journal = Wideochir Inne Tech Maloinwazyjne | volume = 8 | issue = 3 | pages = 183-6 | month = Sep | year = 2013 | doi = 10.5114/wiitm.2011.34205 | PMID = 24130630 }}</ref>
**In a survey of surgeons:
**67% defined it by an anatomical landmark
***35% of all respondants considered the peritoneal reflection the proximal boundary of the rectum.
**30% defined the proximal boundary as a distance from the anal verge.


=Common non-neoplastic disease=
=Common non-neoplastic disease=
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