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Difference between revisions of "Colon"
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replace PBoD
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===Crohn's disease vs. ulcerative colitis=== | ===Crohn's disease vs. ulcerative colitis=== | ||
UC features:<ref>PBoD | UC features:<ref name=Ref_PBoD850>{{Ref PBoD|850}}</ref> | ||
*Mucosal involvement --sometimes submucosa. | *Mucosal involvement --sometimes submucosa. | ||
*No skip lesions. | *No skip lesions. | ||
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===Gross=== | ===Gross=== | ||
Features:<ref>PBoD | Features:<ref name=Ref_PBoD852>{{Ref PBoD|852}}</ref> | ||
*Luminal part (mucosa & submucosa) affected. | *Luminal part (mucosa & submucosa) affected. | ||
*Splenic flexture of colon commonly affected (vascular watershed). | *Splenic flexture of colon commonly affected (vascular watershed). | ||
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Note: | Note: | ||
*May have pseudomembranes (classically assoc. with ''C. difficle'' colitis), i.e. mimics an infectious process. | *May have pseudomembranes (classically assoc. with ''C. difficle'' colitis), i.e. mimics an infectious process. | ||
*DDx for pseudomembranes:<ref>PBoD | *DDx for pseudomembranes:<ref name=Ref_PBoD837-8>{{Ref PBoD|837-8}}</ref> | ||
**C. difficle induced pseudomembranous colitis, | **C. difficle induced pseudomembranous colitis, | ||
**Ischemic colitis, | **Ischemic colitis, | ||
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**... anything that causes severe mucosal injury. | **... anything that causes severe mucosal injury. | ||
Histology of pseudomembranes:<ref>PBoD | Histology of pseudomembranes:<ref name=Ref_PBoD837-8>{{Ref PBoD|837-8}}</ref> | ||
*Loss of surf. epithelium, | *Loss of surf. epithelium, | ||
*PMNs in lamina propria, | *PMNs in lamina propria, | ||
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===Etiology=== | ===Etiology=== | ||
*Thought to be caused by the higher wall tension of cecum (due to larger diameter) and result from (intermittent) venous occulsion/focal dilation of vessels.<ref>PBoD | *Thought to be caused by the higher wall tension of cecum (due to larger diameter) and result from (intermittent) venous occulsion/focal dilation of vessels.<ref name=Ref_PBoD854>{{Ref PBoD|854}}</ref> | ||
==Melanosis coli== | ==Melanosis coli== | ||