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Difference between revisions of "Collagenous colitis"
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = Collagenous_colitis_-_high_mag.jpg | | Image = Collagenous_colitis_-_high_mag.jpg | ||
| Width = | | Width = | ||
| Caption = Collagenous colitis. [[H&E stain]]. | | Caption = Collagenous colitis. [[H&E stain]]. | ||
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==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Intraepithelial lymphocytes - '''important'''. | *[[Intraepithelial lymphocytes]] - '''important'''. | ||
*Collagenous material in the lamina propria (pink on H&E) -- '''key feature'''. | *Collagenous material in the lamina propria (pink on H&E) -- '''key feature'''. | ||
**Can be demonstrated with a trichrome stain -- collagen = green on trichrome. | **Can be demonstrated with a trichrome stain -- collagen = green on trichrome. | ||
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**No crypt distortion. | **No crypt distortion. | ||
*Thickened collagen band uncommon in rectum.<ref name=pmid1740280>{{Cite journal | last1 = Tanaka | first1 = M. | last2 = Mazzoleni | first2 = G. | last3 = Riddell | first3 = RH. | title = Distribution of collagenous colitis: utility of flexible sigmoidoscopy. | journal = Gut | volume = 33 | issue = 1 | pages = 65-70 | month = Jan | year = 1992 | doi = | PMID = 1740280 }}</ref> | *Thickened collagen band uncommon in rectum.<ref name=pmid1740280>{{Cite journal | last1 = Tanaka | first1 = M. | last2 = Mazzoleni | first2 = G. | last3 = Riddell | first3 = RH. | title = Distribution of collagenous colitis: utility of flexible sigmoidoscopy. | journal = Gut | volume = 33 | issue = 1 | pages = 65-70 | month = Jan | year = 1992 | doi = | PMID = 1740280 }}</ref> | ||
*Described in association of [[pseudomembranous colitis|pseudomembranes]].<ref name=pmid14508399>{{Cite journal | last1 = Yuan | first1 = S. | last2 = Reyes | first2 = V. | last3 = Bronner | first3 = MP. | title = Pseudomembranous collagenous colitis. | journal = Am J Surg Pathol | volume = 27 | issue = 10 | pages = 1375-9 | month = Oct | year = 2003 | doi = | PMID = 14508399 }}</ref> | |||
DDx: | DDx: | ||