Clear cell carcinoma of the urinary bladder

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Clear cell carcinoma of the urinary bladder is a rare subtype of primary adenocarcinoma of the urinary bladder.

It is also known as mesonephroid adenocarcinoma of the urinary bladder, adenocarcinoma of bladder, mesonephroid type and mesonephroid carcinoma.

General

  • Extremely rare - 7 cases reported as of 2013.[1]
  • Female predominance (F:M ~ 2:1).[1]

Microscopic

Features:[1]

DDx:

IHC

  • CK7 +ve.
  • CD10 +ve.
  • CA-125 +ve.
  • GATA3 +ve.

Others:

  • ER -ve.
  • PR -ve.
  • CDX2 -ve.
  • AFP -ve.
  • PSA -ve.

See also

References

  1. 1.0 1.1 1.2 Abbas, M.; Kramer, MW.; Wolters, M.; Herrman, TR.; Becker, JU.; Kreipe, HH. (Feb 2013). "Adenocarcinoma of the urinary bladder, mesonephroid type: a rare case.". Rare Tumors 5 (1): e3. doi:10.4081/rt.2013.e3. PMID 23772302.