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Difference between revisions of "Clear cell carcinoma of the urinary bladder"
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Clear cell carcinoma of the urinary bladder (view source)
Revision as of 17:17, 9 January 2017
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
| Width = | |||
| Caption = | |||
| Synonyms = mesonephroid adenocarcinoma, mesonephroid carcinoma | |||
| Micro = | |||
| Subtypes = subtype of [[primary adenocarcinoma of the urinary bladder]] | |||
| LMDDx = [[nephrogenic adenoma]], other subtypes of [[adenocarcinoma of the urinary bladder]], [[urachal carcinoma]], metastatic carcinoma | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[urinary bladder]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = typically female | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = very rare - case reports | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = poor (?) | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Clear cell carcinoma of the urinary bladder''' is a rare subtype of [[primary adenocarcinoma of the urinary bladder]]. | '''Clear cell carcinoma of the urinary bladder''' is a rare subtype of [[primary adenocarcinoma of the urinary bladder]]. | ||
It is also known as '''mesonephroid adenocarcinoma of the urinary bladder''' | It is also known as '''mesonephroid adenocarcinoma of the urinary bladder''', '''adenocarcinoma of bladder, mesonephroid type''' and '''mesonephroid carcinoma'''. | ||
It is described as the malignant counterpart of [[nephrogenic adenoma]].<ref name=pmid17516385>{{Cite journal | last1 = Bannowsky | first1 = A. | last2 = Wefer | first2 = B. | last3 = Osmonov | first3 = D. | last4 = Sotelino | first4 = JA. | last5 = Filippow | first5 = N. | last6 = Naumann | first6 = CM. | last7 = van der Horst | first7 = Ch. | last8 = Jünemann | first8 = KP. | last9 = Hautmann | first9 = S. | title = [Mesonephroid carcinoma of the urinary bladder (clear cell carcinoma). Two case reports and review of the literature in a rare variation of the primary adenocarcinoma]. | journal = Aktuelle Urol | volume = 38 | issue = 3 | pages = 247-51 | month = May | year = 2007 | doi = 10.1055/s-2006-932177 | PMID = 17516385 }}</ref> | |||
==General== | ==General== | ||
*Extremely rare | *Extremely rare. | ||
**7 cases reported as of 2013 according to one study.<ref name=pmid23772302>{{Cite journal | last1 = Abbas | first1 = M. | last2 = Kramer | first2 = MW. | last3 = Wolters | first3 = M. | last4 = Herrman | first4 = TR. | last5 = Becker | first5 = JU. | last6 = Kreipe | first6 = HH. | title = Adenocarcinoma of the urinary bladder, mesonephroid type: a rare case. | journal = Rare Tumors | volume = 5 | issue = 1 | pages = e3 | month = Feb | year = 2013 | doi = 10.4081/rt.2013.e3 | PMID = 23772302 }}</ref> | |||
**19 cases reported as of 2007 according to another study.<ref name=pmid17516385/> | |||
**47 cases reported as of 2014 according to a third study.<ref name=pmid27379325>{{Cite journal | last1 = Venyo | first1 = AK. | title = Primary Clear Cell Carcinoma of the Urinary Bladder. | journal = Int Sch Res Notices | volume = 2014 | issue = | pages = 593826 | month = | year = 2014 | doi = 10.1155/2014/593826 | PMID = 27379325 }}</ref> | |||
*Female predominance (F:M ~ 2:1).<ref name=pmid23772302/> | *Female predominance (F:M ~ 2:1).<ref name=pmid23772302/> | ||
==Microscopic== | ==Microscopic== | ||
Features:<ref name=pmid23772302/> | Features:<ref name=pmid23772302/> | ||
* | *Clear cells with moderate atypia. | ||
**Clear cell component may be minimal. | |||
*Gland forming lesion. | |||
*+/-Hobnailing of lining cells (suggestive). | |||
DDx: | DDx: | ||
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*Other subtypes of [[adenocarcinoma of the urinary bladder]]. | *Other subtypes of [[adenocarcinoma of the urinary bladder]]. | ||
*[[Urachal carcinoma]]. | *[[Urachal carcinoma]]. | ||
*[[Metastasis|Metastatic carcinoma]]. | |||
===Images=== | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682455/figure/F1/ CCC of urinary bladder (nih.gov)].<ref name=pmid23772302/> | |||
==IHC== | ==IHC== | ||
Features: | |||
*CK7 +ve. | *CK7 +ve. | ||
*CD10 +ve. | *CD10 +ve. | ||
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==See also== | ==See also== | ||
*[[Urinary bladder]]. | *[[Urinary bladder]]. | ||
*[[Clear cell adenocarcinoma]]. | |||
==References== | ==References== | ||
{{Reflist|1}} | {{Reflist|1}} | ||
==External links== | |||
*[http://codes.iarc.fr/code/4330 ICD-O (iarc.fr)]. | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Urinary bladder]] | |||