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Chondro-osseous tumours (view source)
Revision as of 17:30, 27 December 2010
, 17:30, 27 December 2010→Chondrosarcoma: expand
(→Chondrosarcoma: +mesenchymal chondrosarcoma) |
(→Chondrosarcoma: expand) |
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==Chondrosarcoma== | ==Chondrosarcoma== | ||
===General=== | |||
Clinical/epidemiologic features:<ref name=pmid17976362>{{cite journal |author=Skubitz KM, D'Adamo DR |title=Sarcoma |journal=Mayo Clin. Proc. |volume=82 |issue=11 |pages=1409–32 |year=2007 |month=November |pmid=17976362 |doi= |url=http://www.mayoclinicproceedings.com/content/82/11/1409.long}}</ref> | |||
*Usually arise in a (benign) abnormality of cartilage (e.g. osteochondroma, enchondroma). | |||
*May be associated with a syndrome: | |||
**Olier disease (multiple enchondromatosis). | |||
**Maffucci syndrome (multiple enchondromas and hemangiomas). | |||
Several subtypes exist: | |||
*Chondrosarcoma not otherwise specified (NOS). | |||
*Juxtacortical chondrosarcoma. | |||
*Myxoid chondrosarcoma. | |||
*Mesenchymal chondrosarcoma. | |||
*Clear cell chondrosarcoma. | |||
*Dedifferentiated chondrosarcoma chondrosarcoma. | |||
===Microscopic=== | ===Microscopic=== | ||
Features:<ref>IAV. 26 February 2009.</ref> | Features:<ref>IAV. 26 February 2009.</ref> | ||
*Abnormal cartilage | *"Abnormal cartilage": | ||
*Nuclear atypia. | **Nuclear atypia. | ||
**Nuclear clearing. | ***Nuclear clearing. | ||
**Nucleoli. | ***Nucleoli. | ||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Chondrosarcoma_(2).jpg Chondrosarcoma (WC)]. | |||
====Mesenchymal chondrosarcoma==== | ====Mesenchymal chondrosarcoma==== | ||