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Difference between revisions of "Chondro-osseous tumours"
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→Giant cell tumour: +image, rename
(→Subtypes: re-arr) |
(→Giant cell tumour: +image, rename) |
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*Drugs (thiazides ... others). | *Drugs (thiazides ... others). | ||
==Giant cell tumour== | ==Giant cell tumour of bone== | ||
===General=== | ===General=== | ||
Features:<ref name=Ref_WMSP648>{{Ref WMSP|648}}</ref> | Features:<ref name=Ref_WMSP648>{{Ref WMSP|648}}</ref> | ||
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*Typical age: 20-45 years. | *Typical age: 20-45 years. | ||
===Clinical=== | ====Clinical==== | ||
*May present with joint pain, immobility. | *May present with joint pain, immobility. | ||
Note: | |||
*Several types of giant cell tumours exist. | |||
===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=Ref_Klatt420>{{Ref Klatt|420}}</ref> | Features:<ref name=Ref_Klatt420>{{Ref Klatt|420}}</ref> | ||
*Giant cells. | *Giant cells with abundant nuclei (usu. >10 in the plane of section). | ||
*Mononuclear cells | **Usu. have prominent nucleoli. | ||
*Mononuclear cells and small multinucleated cells with nuclei similar to those in the giant cells - '''key feature''' | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Giant_cell_tumour_of_bone_-_high_mag.jpg GCT of bone - high mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Giant_cell_tumour_of_bone_-_low_mag.jpg GCT of bone - low mag. (WC)]. | |||
=See also= | =See also= | ||