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Difference between revisions of "Chondro-osseous tumours"
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WMSP
(→See also: SRBCT) |
(WMSP) |
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'''Bone''' occasionally crosses the desk of the pathologist. Primary bone tumours are rare; the most common bone tumour is metastases.<ref>WMSP | '''Bone''' occasionally crosses the desk of the pathologist. Primary bone tumours are rare; the most common bone tumour is metastases.<ref name=Ref_WMSP632>{{Ref WMSP|632}}</ref> | ||
Bone tumours occasionally are lumped with soft tissue tumours. Soft tissue tumours are dealt with in the ''[[soft tissue lesions]]'' article. | Bone tumours occasionally are lumped with soft tissue tumours. Soft tissue tumours are dealt with in the ''[[soft tissue lesions]]'' article. | ||
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===Bone marrow=== | ===Bone marrow=== | ||
*Fat content (%) ~= age (in years)<ref>IAV 26 Feb | *Fat content (%) ~= age (in years)<ref>IAV. 26 Feb 2009.</ref> | ||
**e.g. 60 year old will have 60% fatty replacement. | **e.g. 60 year old will have 60% fatty replacement. | ||
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=Bone tumours= | =Bone tumours= | ||
==General== | ==General== | ||
*Metastasis:primary bone tumours = >20:1.<ref>WMSP | *Metastasis:primary bone tumours = >20:1.<ref name=Ref_WMSP632>{{Ref WMSP|632}}</ref> | ||
===Common malignant=== | ===Common malignant=== | ||
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==Giant cell tumour== | ==Giant cell tumour== | ||
===General=== | ===General=== | ||
Features:<ref>WMSP | Features:<ref name=Ref_WMSP648>{{Ref WMSP|648}}</ref> | ||
*Approximately 5% of primary bone tumours. | *Approximately 5% of primary bone tumours. | ||
*Typical age: 20-45 years. | *Typical age: 20-45 years. | ||
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===Radiology=== | ===Radiology=== | ||
Features:<ref>WMSP | Features:<ref name=Ref_WMSP650>{{Ref WMSP|650}}</ref> | ||
*Long bones, diaphyses. | *Long bones, diaphyses. | ||
*Destructive. | *Destructive. | ||
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===[[IHC]]=== | ===[[IHC]]=== | ||
Features:<ref>WMSP | Features:<ref name=Ref_WMSP651>{{Ref WMSP|651}}</ref> | ||
*CD99 +ve (plasma membrane staining). | *CD99 +ve (plasma membrane staining). | ||
*CD45 -ve. | *CD45 -ve. | ||
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==Adamantinoma== | ==Adamantinoma== | ||
===General=== | ===General=== | ||
Features:<ref>WMSP | Features:<ref name=Ref_WMSP650>{{Ref WMSP|650}}</ref> | ||
*Rare: < 1% of bone tumours. | *Rare: < 1% of bone tumours. | ||
*25-35 years old. | *25-35 years old. | ||