Difference between revisions of "Cholesterol polyp of the gallbladder"

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{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Gallbladder cholesterol polyp -- intermed mag.jpg
| Width      =
| Caption    = Cholesterol polyp of the gallbladder. [[H&E stain]].
| Synonyms  =
| Micro      = foamy macrophages in lamina propria of polypoid lesion
| Subtypes  =
| LMDDx      = [[cholesterolosis of gallbladder]], [[xanthogranulomatous cholecystitis]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      = polypoid lesion of gallbladder mucosa
| Grossing  =
| Staging    =
| Site      = [[gallbladder]]
| Assdx      = [[chronic cholecystitis]]
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = common
| Bloodwork  =
| Rads      = polypoid lesion - projects into lumen of gallbladder
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    = [[gallbladder adenoma]], other polyps
| Tx        = surgical excision (cholecystectomy)
}}
'''Cholesterol polyp of the gallbladder''' is a common benign finding of the [[gallbladder]].
'''Cholesterol polyp of the gallbladder''' is a common benign finding of the [[gallbladder]].


''Cholesterol polyp'' redirects here.
==General==
==General==
*Benign and common.
*Seen in approximately 6% of removed gallbladders.<ref name=pmid23236547>{{Cite journal  | last1 = Terada | first1 = T. | title = Histopathologic features and frequency of gall bladder lesions in consecutive 540 cholecystectomies. | journal = Int J Clin Exp Pathol | volume = 6 | issue = 1 | pages = 91-6 | month =  | year = 2013 | doi =  | PMID = 23236547 }}</ref>
*Seen in approximately 6% of removed gallbladders.<ref name=pmid23236547>{{Cite journal  | last1 = Terada | first1 = T. | title = Histopathologic features and frequency of gall bladder lesions in consecutive 540 cholecystectomies. | journal = Int J Clin Exp Pathol | volume = 6 | issue = 1 | pages = 91-6 | month =  | year = 2013 | doi =  | PMID = 23236547 }}</ref>
*May be detected on ultrasound.<ref name=pmid23233003/>


==Gross==
==Gross==
Line 8: Line 43:


DDx:
DDx:
*[[Gallbladder adenoma]].
*[[Gallbladder adenoma]].<ref name=pmid23233003>{{Cite journal  | last1 = Park | first1 = CH. | last2 = Chung | first2 = MJ. | last3 = Oh | first3 = TG. | last4 = Park | first4 = JY. | last5 = Bang | first5 = S. | last6 = Park | first6 = SW. | last7 = Kim | first7 = H. | last8 = Hwang | first8 = HK. | last9 = Lee | first9 = WJ. | title = Differential diagnosis between gallbladder adenomas and cholesterol polyps on contrast-enhanced harmonic endoscopic ultrasonography. | journal = Surg Endosc | volume = 27 | issue = 4 | pages = 1414-21 | month = Apr | year = 2013 | doi = 10.1007/s00464-012-2620-x | PMID = 23233003 }}</ref>


==Microscopic==
==Microscopic==
Features:
Features:
*Foamy macrophages in the lamina propria.
*Foamy macrophages in the lamina propria.
*Polypoid shape - epithelium on three sides.


DDx:
DDx:
*[[Xanthogranulomatous cholecystitis]].
*[[Xanthogranulomatous cholecystitis]].
*[[Cholesterolosis of gallbladder]] - not polypoid.
===Images===
<gallery>
Image: Gallbladder cholesterol polyp -- very low mag.jpg | CP - very low mag. (WC)
Image: Gallbladder cholesterol polyp -- low mag.jpg | CP - low mag. (WC)
Image: Gallbladder cholesterol polyp -- intermed mag.jpg | CP - intermed. mag. (WC) 
Image: Gallbladder cholesterol polyp -- high mag.jpg | CP - high mag. (WC)
</gallery>


==See also==
==See also==

Latest revision as of 13:02, 31 May 2016

Cholesterol polyp of the gallbladder
Diagnosis in short

Cholesterol polyp of the gallbladder. H&E stain.

LM foamy macrophages in lamina propria of polypoid lesion
LM DDx cholesterolosis of gallbladder, xanthogranulomatous cholecystitis
Gross polypoid lesion of gallbladder mucosa
Site gallbladder

Associated Dx chronic cholecystitis
Prevalence common
Radiology polypoid lesion - projects into lumen of gallbladder
Prognosis benign
Clin. DDx gallbladder adenoma, other polyps
Treatment surgical excision (cholecystectomy)

Cholesterol polyp of the gallbladder is a common benign finding of the gallbladder.

Cholesterol polyp redirects here.

General

  • Benign and common.
  • Seen in approximately 6% of removed gallbladders.[1]
  • May be detected on ultrasound.[2]

Gross

  • Exophytic lesion of the gallbladder mucosa.

DDx:

Microscopic

Features:

  • Foamy macrophages in the lamina propria.
  • Polypoid shape - epithelium on three sides.

DDx:

Images

See also

References

  1. Terada, T. (2013). "Histopathologic features and frequency of gall bladder lesions in consecutive 540 cholecystectomies.". Int J Clin Exp Pathol 6 (1): 91-6. PMID 23236547.
  2. 2.0 2.1 Park, CH.; Chung, MJ.; Oh, TG.; Park, JY.; Bang, S.; Park, SW.; Kim, H.; Hwang, HK. et al. (Apr 2013). "Differential diagnosis between gallbladder adenomas and cholesterol polyps on contrast-enhanced harmonic endoscopic ultrasonography.". Surg Endosc 27 (4): 1414-21. doi:10.1007/s00464-012-2620-x. PMID 23233003.