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Difference between revisions of "Cholesterol embolism"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Cholesterol embolus - high mag.jpg | |||
| Width = | |||
| Caption = Cholesterol embolism. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = intravascular cholesterol clefts (biconvex white spaces), +/-macrophages and giant cells, +/-eosinophils | |||
| Subtypes = | |||
| LMDDx = | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[blood vessels]] - arteries | |||
| Assdx = [[atherosclerosis]] | |||
| Syndromes = | |||
| Clinicalhx = +/-cardiovascular intervention, +/-cardiovascular disease, +/-risk factors for cardiovascular disease (age, [[hypertension]], hypercholesterolemia, [[diabetes mellitus|diabetes]], [[smoking]]) | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = not typically biopsied, common in eldery | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = dependent on extent | |||
| Other = | |||
| ClinDDx = [[vasculitis]] | |||
| Tx = | |||
}} | |||
'''Cholesterol embolism''', abbreviated '''CE''', is characterized by intravascular cholesterol. | '''Cholesterol embolism''', abbreviated '''CE''', is characterized by intravascular cholesterol. | ||
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*Significant CEs are often iatrogenic. | *Significant CEs are often iatrogenic. | ||
**Known complication of coronary catherization (incidence ~ 1%).<ref name=pmid12875753>{{cite journal |author=Fukumoto Y, Tsutsui H, Tsuchihashi M, Masumoto A, Takeshita A |title=The incidence and risk factors of cholesterol embolization syndrome, a complication of cardiac catheterization: a prospective study |journal=J. Am. Coll. Cardiol. |volume=42 |issue=2 |pages=211–6 |year=2003 |month=July |pmid=12875753 |doi=10.1016/S0735-1097(03)00579-5 | url=http://linkinghub.elsevier.com/retrieve/pii/S0735109703005795}}</ref> | **Known complication of coronary catherization (incidence ~ 1%).<ref name=pmid12875753>{{cite journal |author=Fukumoto Y, Tsutsui H, Tsuchihashi M, Masumoto A, Takeshita A |title=The incidence and risk factors of cholesterol embolization syndrome, a complication of cardiac catheterization: a prospective study |journal=J. Am. Coll. Cardiol. |volume=42 |issue=2 |pages=211–6 |year=2003 |month=July |pmid=12875753 |doi=10.1016/S0735-1097(03)00579-5 | url=http://linkinghub.elsevier.com/retrieve/pii/S0735109703005795}}</ref> | ||
**May complicate any vascular surgery, CABG. | **May complicate any vascular surgery, [[CABG]]. | ||
==Microscopic== | ==Microscopic== | ||
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Image:Cholesterol_embolus_-_intermed_mag.jpg | Cholesterol embolus - intermed. mag. (WC) | Image:Cholesterol_embolus_-_intermed_mag.jpg | Cholesterol embolus - intermed. mag. (WC) | ||
Image:Cholesterol_embolus_-_high_mag.jpg | Cholesterol embolus - high mag. (WC) | Image:Cholesterol_embolus_-_high_mag.jpg | Cholesterol embolus - high mag. (WC) | ||
Image: Cholesterol embolus - very high mag.jpg | Cholesterol embolus - very high mag. (WC) | |||
</gallery> | </gallery> | ||