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Difference between revisions of "Cholangiocarcinoma"
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| LMDDx = [[metastatic carcinoma]] - esp. luminal GI tract, [[hepatocellular carcinoma]] | | LMDDx = [[metastatic carcinoma]] - esp. luminal GI tract, [[hepatocellular carcinoma]] | ||
| Stains = | | Stains = | ||
| IHC = CK7 +ve, [[CK20]] +ve/-ve, [[CK19]] +ve, HepPar-1 -ve, AFP -ve, EMA +ve | | IHC = CK7 +ve, [[CK20]] +ve/-ve, [[CK19]] +ve, HepPar-1 -ve, [[AFP]] -ve, [[EMA]] +ve | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
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==IHC== | ==IHC== | ||
Classic IHC pattern:<ref>{{Ref GLP|609}}</ref> | Classic IHC pattern:<ref>{{Ref GLP|609}}</ref> | ||
*CK7 +ve. | *[[CK7]] +ve. | ||
*CK20 +ve/-ve. | *[[CK20]] +ve/-ve. | ||
*HepPar-1 -ve. | *HepPar-1 -ve. | ||
*AFP -ve.<ref name=stc6dec2010>STC. 6 December 2010.</ref> | *[[AFP]] -ve.<ref name=stc6dec2010>STC. 6 December 2010.</ref> | ||
ICC vs. HCC:<ref name=pmid19173916>[Evaluation of immunohistochemical markers for differential diagnosis of hepatocellular carcinoma from intrahepatic cholangiocarcinoma] Dong H, Cong WL, Zhu ZZ, Wang B, Xian ZH, Yu H. Zhonghua Zhong Liu Za Zhi. 2008 Sep;30(9):702-5. Chinese. PMID 19173916.</ref> | ICC vs. HCC:<ref name=pmid19173916>[Evaluation of immunohistochemical markers for differential diagnosis of hepatocellular carcinoma from intrahepatic cholangiocarcinoma] Dong H, Cong WL, Zhu ZZ, Wang B, Xian ZH, Yu H. Zhonghua Zhong Liu Za Zhi. 2008 Sep;30(9):702-5. Chinese. PMID 19173916.</ref> | ||