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Difference between revisions of "Cholangiocarcinoma"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Cholangiocarcinoma_-_high_mag.jpg | |||
| Width = | |||
| Caption = Cholangiocarcinoma. [[H&E stain]]. | |||
| Synonyms = bile duct carcinoma | |||
| Micro = atypical cuboidal or columnar mucin producing cohesive cells (carcinoma) - usually gland forming ([[adenocarcinoma]]), classically with a dense fibrous ([[desmoplastic stroma|desmoplastic]]) stroma | |||
| Subtypes = | |||
| LMDDx = [[metastatic carcinoma]] - esp. luminal GI tract, [[hepatocellular carcinoma]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = bile ducts (including pancreas, [[liver]] - see ''[[liver neoplasms]]'') | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = +/-jaundice | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = +/-findings of cholestasis | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = poor | |||
| Other = | |||
| ClinDDx = other liver tumours - [[hepatocellular carcinoma]], [[metastases]] | |||
| Tx = surgical resection if possible | |||
}} | |||
'''Cholangiocarcinoma''' is a [[malignant]] tumour that arise from the bile ducts and may been seen in the [[liver neoplasms|liver]]. | '''Cholangiocarcinoma''' is a [[malignant]] tumour that arise from the bile ducts and may been seen in the [[liver neoplasms|liver]]. | ||
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<gallery> | <gallery> | ||
Image:Cholangiocarcinoma_-_low_mag.jpg | Cholangiocarcinoma - low mag. Shows the typical [[desmoplastic stroma]]. (WC/Nephron) | Image:Cholangiocarcinoma_-_low_mag.jpg | Cholangiocarcinoma - low mag. Shows the typical [[desmoplastic stroma]]. (WC/Nephron) | ||
Image:Cholangiocarcinoma - intermed mag.jpg | Cholangiocarcinoma - intermed. mag. (WC/Nephron) | |||
Image:Cholangiocarcinoma_-_high_mag.jpg |Cholangiocarcinoma - high mag. Shows a normal portal triad adjacent to atypical glandular cells within the interlobular septum and obvious tumour. (WC/Nephron) | Image:Cholangiocarcinoma_-_high_mag.jpg |Cholangiocarcinoma - high mag. Shows a normal portal triad adjacent to atypical glandular cells within the interlobular septum and obvious tumour. (WC/Nephron) | ||
Image:Cholangiocarcinoma - very high mag.jpg | Cholangiocarcinoma - very high mag. (WC/Nephron) | |||
</gallery> | </gallery> | ||
www: | www: | ||