Difference between revisions of "Central neurocytoma"

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#redirect [[Neuropathology tumours#Central neurocytoma]]
'''Central neurocytoma''', abbreviated '''CNC''', is a rare [[neuropathology tumour]].
 
==General==
*Rare - less than 1% of brain tumours.<ref name=pmid16163043>{{Cite journal  | last1 = Chuang | first1 = MT. | last2 = Lin | first2 = WC. | last3 = Tsai | first3 = HY. | last4 = Liu | first4 = GC. | last5 = Hu | first5 = SW. | last6 = Chiang | first6 = IC. | title = 3-T proton magnetic resonance spectroscopy of central neurocytoma: 3 case reports and review of the literature. | journal = J Comput Assist Tomogr | volume = 29 | issue = 5 | pages = 683-8 | month =  | year =  | doi =  | PMID = 16163043 }}</ref>
*Benign.
*First described in 1982.<ref name=pmid16163043/>
 
==Gross/radiology==
*Intraventricular.<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/Com/Com307-1-Diss.htm http://moon.ouhsc.edu/kfung/jty1/Com/Com307-1-Diss.htm]. Accessed on: 12 January 2012.</ref>
**Characteristically attached to the ''septum pellucidum''.<ref name=pmid20692674>{{Cite journal  | last1 = Kerkeni | first1 = A. | last2 = Ben Lakhdher | first2 = Z. | last3 = Rkhami | first3 = M. | last4 = Sebai | first4 = R. | last5 = Belguith | first5 = L. | last6 = Khaldi | first6 = M. | last7 = Ben Hamouda | first7 = M. | title = [Central neurocytoma: Study of 32 cases and review of the literature]. | journal = Neurochirurgie | volume = 56 | issue = 5 | pages = 408-14 | month = Oct | year = 2010 | doi = 10.1016/j.neuchi.2010.07.001 | PMID = 20692674 }}</ref>
 
==Microscopic==
Features:<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/Com/Com307-1-Diss.htm http://moon.ouhsc.edu/kfung/jty1/Com/Com307-1-Diss.htm]. Accessed on: 27 May 2011.</ref>
*Perivascular pseudorosette = circular/flower-like arrangement of cells with blood vessel at the centre.<ref name=pmid16551982>{{cite journal |author=Wippold FJ, Perry A |title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes |journal=AJNR Am J Neuroradiol |volume=27 |issue=3 |pages=488–92 |year=2006 |month=March |pmid=16551982 |doi= |url=}}</ref>
*Islands of neuropil.
*Polygonal cells with a perinuclear halo.
 
DDx:
*[[Oligodendroglioma]].
 
DDx of perivascular pseudorosette:
*Ependymoma.
*[[Medulloblastoma]], PNET.
*[[Glioblastoma]]s.
 
===Images===
<gallery>
Image:Central_neurocytoma_-_intermed_mag.jpg | Central neurocytoma - intermed. mag. (WC)
Image:Central_neurocytoma_-_high_mag.jpg | Central neurocytoma - oligodendrogllioma-like area - high mag. (WC)
Image:Central_neurocytoma_-_2_-_high_mag.jpg | Central neurocytoma - pseudorosettes - high mag. (WC)
Image:Central_neurocytoma_-_2_-_very_high_mag.jpg | Central neurocytoma - pseudorossettes - very high mag. (WC)
</gallery>
[[www]]:
*[http://moon.ouhsc.edu/kfung/jty1/Com/Com307-1-Diss.htm Central neurocytoma - several images (ouhsc.edu)].
*[http://frontalcortex.com/?page=image&topic=1&qid=1203 Central neurocytoma (frontalcortex.com)].
*[http://path.upmc.edu/cases/case74/micro.html Central neurocytoma - crappy images (upmc.edu)].
 
==IHC==
*MIB1 - high may predict re-occurance.<ref name=pmid15015671>{{Cite journal  | last1 = Schmidt | first1 = MH. | last2 = Gottfried | first2 = ON. | last3 = von Koch | first3 = CS. | last4 = Chang | first4 = SM. | last5 = McDermott | first5 = MW. | title = Central neurocytoma: a review. | journal = J Neurooncol | volume = 66 | issue = 3 | pages = 377-84 | month = Feb | year = 2004 | doi =  | PMID = 15015671 }}</ref>
 
==See also==
*[[Neuropathology tumours]].
 
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Neuropathology tumours]]

Latest revision as of 06:24, 10 December 2014

Central neurocytoma, abbreviated CNC, is a rare neuropathology tumour.

General

  • Rare - less than 1% of brain tumours.[1]
  • Benign.
  • First described in 1982.[1]

Gross/radiology

  • Intraventricular.[2]
    • Characteristically attached to the septum pellucidum.[3]

Microscopic

Features:[4]

  • Perivascular pseudorosette = circular/flower-like arrangement of cells with blood vessel at the centre.[5]
  • Islands of neuropil.
  • Polygonal cells with a perinuclear halo.

DDx:

DDx of perivascular pseudorosette:

Images

  • Central neurocytoma - intermed. mag. (WC)

  • Central neurocytoma - oligodendrogllioma-like area - high mag. (WC)

  • Central neurocytoma - pseudorosettes - high mag. (WC)

  • Central neurocytoma - pseudorossettes - very high mag. (WC)

www:

IHC

  • MIB1 - high may predict re-occurance.[6]

See also

References

  1. ↑ 1.0 1.1 Chuang, MT.; Lin, WC.; Tsai, HY.; Liu, GC.; Hu, SW.; Chiang, IC.. "3-T proton magnetic resonance spectroscopy of central neurocytoma: 3 case reports and review of the literature.". J Comput Assist Tomogr 29 (5): 683-8. PMID 16163043.
  2. ↑ URL: http://moon.ouhsc.edu/kfung/jty1/Com/Com307-1-Diss.htm. Accessed on: 12 January 2012.
  3. ↑ Kerkeni, A.; Ben Lakhdher, Z.; Rkhami, M.; Sebai, R.; Belguith, L.; Khaldi, M.; Ben Hamouda, M. (Oct 2010). "[Central neurocytoma: Study of 32 cases and review of the literature].". Neurochirurgie 56 (5): 408-14. doi:10.1016/j.neuchi.2010.07.001. PMID 20692674.
  4. ↑ URL: http://moon.ouhsc.edu/kfung/jty1/Com/Com307-1-Diss.htm. Accessed on: 27 May 2011.
  5. ↑ Wippold FJ, Perry A (March 2006). "Neuropathology for the neuroradiologist: rosettes and pseudorosettes". AJNR Am J Neuroradiol 27 (3): 488–92. PMID 16551982.
  6. ↑ Schmidt, MH.; Gottfried, ON.; von Koch, CS.; Chang, SM.; McDermott, MW. (Feb 2004). "Central neurocytoma: a review.". J Neurooncol 66 (3): 377-84. PMID 15015671.
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