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Difference between revisions of "Case 5"
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===Clinical history=== | ===Clinical history=== | ||
68 year old woman, cerebellar mass. | 68 year old woman, cerebellar mass. | ||
===Primary image=== | ===Primary image=== | ||
[[Image:Metastatic adenocarcinoma - cerebellum - very low mag.jpg|500px|link=|center|]] | [[Image:Metastatic adenocarcinoma - cerebellum - very low mag.jpg|500px|link=|center|]] | ||
<center>Very low magnification. [[ | <center>Very low magnification. [[HPS stain]].</center> | ||
{{hidden|Intermediate magnification|[[Image:Metastatic adenocarcinoma - cerebellum - intermed mag.jpg|500px|link=|center|]] | {{hidden|Intermediate magnification|[[Image:Metastatic adenocarcinoma - cerebellum - intermed mag.jpg|500px|link=|center|]] | ||
<center>Intermediate magnification. [[ | <center>Intermediate magnification. [[HPS stain]].</center>}} | ||
{{hidden|High magnification|[[Image:Metastatic adenocarcinoma - cerebellum - high mag.jpg|500px|link=|center|]] | {{hidden|High magnification|[[Image:Metastatic adenocarcinoma - cerebellum - high mag.jpg|500px|link=|center|]] | ||
<center>High magnification. [[ | <center>High magnification. [[HPS stain]].</center>}} | ||
===Differential diagnosis=== | ===Differential diagnosis=== | ||
| Line 17: | Line 17: | ||
===Additional tests=== | ===Additional tests=== | ||
====More history==== | ====More history==== | ||
{{hidden|More history|<center>Patient has had really bad headaches and vomiting. Constipated. Smoker since teens.</center>}} | {{hidden|More history|<center>Patient has had really bad headaches and vomiting. Constipated. Smoker since teens - 1 ppd.</center>}} | ||
====Ask a friend==== | ====Ask a friend==== | ||
{{hidden|Ask a friend|<center>Reminds me of a [[TA|tubular adenoma]].</center>}} | {{hidden|Ask a friend|<center>Reminds me of a [[TA|tubular adenoma]]. You'll need to do IHC.</center>}} | ||
====Stains==== | ====Stains==== | ||
| Line 72: | Line 72: | ||
| afp= | | afp= | ||
| alk1= | | alk1= | ||
| amacr= | | amacr= | ||
| | | ar= | ||
| | | b2microglobulin= | ||
| b72_3= | |||
| bcatenin= | |||
| bcl2= | | bcl2= | ||
| bcl6= | | bcl6= | ||
| bclxl= | | bclxl= | ||
| c3= | | c3= | ||
| | | calcitonin= | ||
| calponin= | | calponin= | ||
| calretinin= | | calretinin= | ||
| cam5p2= | |||
| cd10= | | cd10= | ||
| cd117= | | cd117= | ||
| cd138= | |||
| cd15= | | cd15= | ||
| cd1a= | | cd1a= | ||
| Line 96: | Line 100: | ||
| cd4= | | cd4= | ||
| cd43= | | cd43= | ||
| cd45= | |||
| cd45= | | cd45= | ||
| cd5= | | cd5= | ||
| Line 104: | Line 109: | ||
| cd8= | | cd8= | ||
| cd99= | | cd99= | ||
| cdx2= '''POSITIVE''' | |||
| cea= | | cea= | ||
| chromo= | | chromo= | ||
| chromo= | |||
| ck17= | |||
| ck19= | | ck19= | ||
| ck20= '''POSITIVE''' | | ck20= '''POSITIVE''' | ||
| ck34be12= | | ck34be12= | ||
| ck5_6= | |||
| ck7= '''NEGATIVE''' | | ck7= '''NEGATIVE''' | ||
| cmv= | | cmv= | ||
| cmyc= | | cmyc= | ||
| | | cyclin_d1= | ||
| desmin= | | desmin= | ||
| dog1= | |||
| ebv= | | ebv= | ||
| ema= | | ema= | ||
| erpr= '''NEGATIVE''' | | erpr= BOTH '''NEGATIVE''' | ||
| f_viii= | |||
| f_xiiia= | |||
| fascin= | | fascin= | ||
| fsh= | | fsh= | ||
| gastrin= | | gastrin= | ||
| gcdfp= | | gcdfp= | ||
| gfap= | |||
| gh= | | gh= | ||
| | | glucagon= | ||
| hbme1= | | hbme1= | ||
| | | hbv_core= | ||
| | | hbv_surf= | ||
| hcaldesmon= | |||
| hcg= | | hcg= | ||
| helicobacter= | |||
| hepatocyte= | | hepatocyte= | ||
| her2= | | her2= | ||
| hhv8= | |||
| hmb45= | | hmb45= | ||
| hnf1beta= | |||
| hpv= | | hpv= | ||
| hsv1= | | hsv1= | ||
| hsv2= | | hsv2= | ||
| Idh-1= | |||
| inhibin= | | inhibin= | ||
| insulin= | | insulin= | ||
| Line 140: | Line 156: | ||
| ki67= | | ki67= | ||
| lambda= | | lambda= | ||
| leu7= | | leu7= | ||
| lga= | | lga= | ||
| Line 147: | Line 162: | ||
| lh= | | lh= | ||
| lysozyme= | | lysozyme= | ||
| | | mammogl= | ||
| melanin_a= | |||
| mitf= | |||
| myleoperox= | | myleoperox= | ||
| | | myo_d1= | ||
| myog= | | myog= | ||
| myog= | | myog= | ||
| nf= | |||
| nse= | | nse= | ||
| oct3_4= | |||
| p16= | |||
| p53= | | p53= | ||
| p63= | | p63= | ||
| panker= | | panker= | ||
| pax2= | |||
| pax5= | |||
| pax8= | |||
| pcna= | | pcna= | ||
| pdgfr= | |||
| plap= | | plap= | ||
| | | pnl-2c= | ||
| | | prolactin= | ||
| psa= | | psa= | ||
| psap= | |||
| s100= | | s100= | ||
| sma= | | sma= | ||
| | | somatsatin= | ||
| synapto= | | synapto= | ||
| tdt= | | tdt= | ||
| tfe3= | |||
| thyrogl= | | thyrogl= | ||
| toxopl= | | toxopl= | ||
| Line 172: | Line 198: | ||
| ubiquitin= | | ubiquitin= | ||
| uchl1= | | uchl1= | ||
| | | ulex_europe= | ||
| vim= | | vim= | ||
| vip= | | vip= | ||
| vzv= | | vzv= | ||
| wt1= | |||
}} | }} | ||
===Diagnosis=== | ===Diagnosis=== | ||
{{hidden|Diagnosis|<center>[[Metastatic]] [[colorectal adenocarcinoma]].</center>}} | {{hidden|Diagnosis|<center>[[Metastatic]] [[colorectal adenocarcinoma]].</center>}} | ||
<br> | |||
===Other cases=== | |||
{{Cases navigation|state=collapsed}} | |||
__NOTOC__ | __NOTOC__ | ||
[[Category:Cases]] | [[Category:Cases]] | ||
[[Category:Cases in neuropathology]] | |||
[[Category:Cases difficulty 3]] | |||
[[Category:Cases in neuropathology - junior]] | |||