Difference between revisions of "Case 48"

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193 bytes added ,  18:55, 12 September 2014
 
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===Provided clinical history===
===Provided clinical history===
46 year old male, ascending colon, diffuse brown-black pigmented lesion
46 year old male, pigmentation proximal colon


===Site===
===Site===
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===Differential diagnosis===
===Differential diagnosis===
{{hidden|Differential diagnosis|<center>[[Pseudomelanosis]], [[Hemochromatosis]], [[Melanosis coli]], [[Melanoma]].</center>}}
{{hidden|Differential diagnosis|<center>[[Hemochromatosis]], [[Melanosis coli]], [[Malignant melanoma]].</center>}}


===Additional tests===
===Additional tests===
====More history====
====More history====
{{hidden|More history|<center>Patient has a history of laxative abuse.</center>}}
{{hidden|More history|<center>Colonscopy shows diffuse brown pigmentation in a moire pattern, predominantly in the left colon. Patient complains of constipation. The medications include Effexor, Senokot and Altace.</center>}}


====Ask a colleague====
====Ask a colleague====
{{hidden|Ask a colleague|<center>The brown pigments are not melanin, they are Lipofuscin.</center>}}
{{hidden|Ask a colleague|<center>The brown pigmentation isn't melanin. This finding is worth reporting, especially in the context of IBD, as it can occasionally mimic a colitis.</center>}}


====Stains====
====Stains====
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| biel=  
| biel=  
| bili=  
| bili=  
| iron= -ve
| iron=  
| congored=  
| congored=  
| cresylv=  
| cresylv=  
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| zn=  
| zn=  
}}
}}
====IHC====
====IHC====
{{Case IHC
{{Case IHC
48,460

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