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Difference between revisions of "Case 30"
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===Provided clinical history=== | ===Provided clinical history=== | ||
30 year old woman, | 30 year old woman, anasarca and renal failure | ||
===Site=== | ===Site=== | ||
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[[Image: Membranous_nephropathy_-_mpas_-_high_mag.jpg |500px|link=|center|]] | [[Image: Membranous_nephropathy_-_mpas_-_high_mag.jpg |500px|link=|center|]] | ||
<center>High magnification. [[ | <center>High magnification. [[Jones stain]].</center> | ||
{{hidden|Very high magnification|[[Image: Membranous nephropathy - cropped - mpas - very high mag.jpg |500px|link=|center|]] | {{hidden|Very high magnification|[[Image: Membranous nephropathy - cropped - mpas - very high mag.jpg |500px|link=|center|]] | ||
<center>Very high magnification. [[ | <center>Very high magnification. [[Jones stain]].</center>}} | ||
===Additional tests=== | ===Additional tests=== | ||
====More history==== | ====More history==== | ||
{{hidden|More history|<center>ANA | {{hidden|More history|<center>Proteinuria (4 g/24h), hypercholesterolemia, hypoalbuminemia, ANA -ve, Anti-Sm -ve, Anti-dsDNA -ve, HBV core -ve, HBV surf +ve, HCV -ve, no history of cancer.</center>}} | ||
==== | ====Immunofluorescence==== | ||
{{hidden| | {{hidden|IF|<center>Diffuse granular capillary loop - IgG, C3, kappa, lambda.</center>}} | ||
====Electron microscopy==== | |||
{{hidden|EM|<center>Diffuse subepithelial deposits - spike forming.</center>}} | |||
====Stains==== | ====Stains==== | ||
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| warthinstarry= | | warthinstarry= | ||
}} | }} | ||
====IHC==== | ====IHC==== | ||
{{Case IHC | {{Case IHC | ||
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}} | }} | ||
==== | ====Ask a colleague==== | ||
{{ | {{hidden|Ask a colleague|<center>It is a [[nephrotic syndrome]]. It doesn't look like [[FSGS]] or [[minimal change disease]]... so, it's what is left.</center>}} | ||
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}} | |||
===Diagnosis=== | ===Diagnosis=== | ||
{{hidden|Diagnosis|<center>[[Membranous nephropathy]]</center>}} | {{hidden|Diagnosis|<center>[[Membranous nephropathy]] - probably idiopathic</center>}} | ||
<br> | <br> | ||
===Other cases=== | ===Other cases=== | ||
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[[Category:Cases in medical kidney pathology]] | [[Category:Cases in medical kidney pathology]] | ||
[[Category:Cases difficulty 5]] | [[Category:Cases difficulty 5]] | ||
[[Category:Cases in medical kidney pathology - senior]] | |||