Difference between revisions of "Case 117"

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===Differential diagnosis===
===Differential diagnosis===
{{hidden|Differential diagnosis|<center>Leiomyosarcoma</center>}}
{{hidden|Differential diagnosis|<center>[[Leiomyosarcoma]]</center>}}


===Additional tests===
===Additional tests===
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===Diagnosis===
===Diagnosis===
{{hidden|Diagnosis|<center>ATYPICAL LEIOMYOMA WITH BIZARRE NUCLEI. This smooth muscle tumor shows markedly atypical nuclei, some of which are multinucleate. The nuclei are smudgy and hyperchromatic, raising concern.  However, here is no increase in mitotic activity; necrosis is absent.  The edge of the tumor is rounded and there is no invasion of surrounding myometrium.  These lesions are benign. {{Cite journal  | last1 = Ly | first1 = A. | last2 = Mills | first2 = AM. | last3 = McKenney | first3 = JK. | last4 = Balzer | first4 = BL. | last5 = Kempson | first5 = RL. | last6 = Hendrickson | first6 = MR. | last7 = Longacre | first7 = TA. | title = Atypical leiomyomas of the uterus: a clinicopathologic study of 51 cases. | journal = Am J Surg Pathol | volume = 37 | issue = 5 | pages = 643-9 | month = May | year = 2013 | doi = 10.1097/PAS.0b013e3182893f36 | PMID = 23552381 }} {{Cite journal  | last1 = Croce | first1 = S. | last2 = Young | first2 = RH. | last3 = Oliva | first3 = E. | title = Uterine leiomyomas with bizarre nuclei: a clinicopathologic study of 59 cases. | journal = Am J Surg Pathol | volume = 38 | issue = 10 | pages = 1330-9 | month = Oct | year = 2014 | doi = 10.1097/PAS.0000000000000249 | PMID = 25140893 }}
{{hidden|Diagnosis|<center>[[symplastic leiomyoma|ATYPICAL LEIOMYOMA WITH BIZARRE NUCLEI]]</center>
</center>}}
<br>  
This smooth muscle tumor shows markedly atypical nuclei, some of which are multinucleate. The nuclei are smudgy and hyperchromatic, raising concern.  However, here is no increase in mitotic activity; necrosis is absent.  The edge of the tumor is rounded and there is no invasion of surrounding myometrium.  These lesions are benign.<ref>{{Cite journal  | last1 = Ly | first1 = A. | last2 = Mills | first2 = AM. | last3 = McKenney | first3 = JK. | last4 = Balzer | first4 = BL. | last5 = Kempson | first5 = RL. | last6 = Hendrickson | first6 = MR. | last7 = Longacre | first7 = TA. | title = Atypical leiomyomas of the uterus: a clinicopathologic study of 51 cases. | journal = Am J Surg Pathol | volume = 37 | issue = 5 | pages = 643-9 | month = May | year = 2013 | doi = 10.1097/PAS.0b013e3182893f36 | PMID = 23552381 }}</ref><ref>{{Cite journal  | last1 = Croce | first1 = S. | last2 = Young | first2 = RH. | last3 = Oliva | first3 = E. | title = Uterine leiomyomas with bizarre nuclei: a clinicopathologic study of 59 cases. | journal = Am J Surg Pathol | volume = 38 | issue = 10 | pages = 1330-9 | month = Oct | year = 2014 | doi = 10.1097/PAS.0000000000000249 | PMID = 25140893 }}</ref>
===References===
{{Reflist|1}}
}}
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===Other cases===
===Other cases===
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[[Category:Cases]]
[[Category:Cases]]


<!-- SELECT A CATEGORY
[[Category:Cases in gynecologic pathology]]
[[Category:Cases in gynecologic pathology]]
-->
[[Category:Cases in gynecologic pathology - junior]]
 


[[Category:Cases difficulty 2]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level -->
[[Category:Cases difficulty 2]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level -->
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