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Difference between revisions of "Breast cytopathology"
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(→Ductal carcinoma: yes) |
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| Flat sheets & fluffy paucicellular (fibrous) tissue | | Flat sheets & fluffy paucicellular (fibrous) tissue | ||
| '''Mixed pop. in cluster'''; nuclei: oval/spindle (myoepi.) and round (epi.). | | '''Mixed pop. in cluster'''; nuclei: oval/spindle (myoepi.) and round (epi.). | ||
| [ | | [[Image:Breast_fibroadenoma_by_fine_needle_aspiration_%282%29_PAP_stain.jpg | thumb | 150px | center | Fibroadenoma - FNA (WC)]] | ||
|- | |- | ||
| Fibrocystic change | | Fibrocystic change | ||
| Line 54: | Line 54: | ||
| May have flat sheets of cells | | May have flat sheets of cells | ||
| Oncocytic change (apocrine change) common, histocytes (foamy cytoplasm), [[nucleoli]], large NCR | | Oncocytic change (apocrine change) common, histocytes (foamy cytoplasm), [[nucleoli]], large NCR | ||
| [ | | [[Image:Fibrocystic_changes_of_breast_-_cytology_1.jpg |thumb|150px | center | Oncocytes in FCC. (WC)]] | ||
|- | |- | ||
| Papillary neoplasm | | Papillary neoplasm | ||
| Line 60: | Line 60: | ||
| Sheets, usu. flat? | | Sheets, usu. flat? | ||
| Variable size, nucleolus | | Variable size, nucleolus | ||
| [ | | [[Image:Breast_papillary_neoplasm_1.jpg|thumb|150px| center | Papillary neoplasm. (WC)]] | ||
|- | |- | ||
| Ductal carcinoma | | Ductal carcinoma | ||
| Line 66: | Line 66: | ||
| '''3-D clusters''' | | '''3-D clusters''' | ||
| Nuclear size variation, '''membrane irreg.''', nucleoli (prominent) - every cell, cell size var. | | Nuclear size variation, '''membrane irreg.''', nucleoli (prominent) - every cell, cell size var. | ||
| [ | | [[Image:Ductal_carcinoma_2_-_cytology.jpg |thumb|150px |center | Ductal carcinoma. (WC)]] | ||
|} | |} | ||
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*Myospherulosis - due to exposure to fat, may be seen in the context of malignancy.<ref name=pmid11035579>{{Cite journal | last1 = Chau | first1 = KY. | last2 = Pretorius | first2 = JM. | last3 = Stewart | first3 = AW. | title = Myospherulosis in renal cell carcinoma. | journal = Arch Pathol Lab Med | volume = 124 | issue = 10 | pages = 1476-9 | month = Oct | year = 2000 | doi = 10.1043/0003-9985(2000)1241476:MIRCC2.0.CO;2 | PMID = 11035579 }}</ref> | *Myospherulosis - due to exposure to fat, may be seen in the context of malignancy.<ref name=pmid11035579>{{Cite journal | last1 = Chau | first1 = KY. | last2 = Pretorius | first2 = JM. | last3 = Stewart | first3 = AW. | title = Myospherulosis in renal cell carcinoma. | journal = Arch Pathol Lab Med | volume = 124 | issue = 10 | pages = 1476-9 | month = Oct | year = 2000 | doi = 10.1043/0003-9985(2000)1241476:MIRCC2.0.CO;2 | PMID = 11035579 }}</ref> | ||
Images | ====Images==== | ||
*[http://www.ajronline.org/content/192/3/815/F1.expansion.html Early fat necrosis (ajronline.org)]. | *[http://www.ajronline.org/content/192/3/815/F1.expansion.html Early fat necrosis (ajronline.org)]. | ||
*[http://www.ajronline.org/content/192/3/815/F4.expansion.html Mid fat necrosis (ajronline.org)]. | *[http://www.ajronline.org/content/192/3/815/F4.expansion.html Mid fat necrosis (ajronline.org)]. | ||
| Line 176: | Line 176: | ||
***Nuclei typically ovoid, may be spindle-shaped. | ***Nuclei typically ovoid, may be spindle-shaped. | ||
Images | ====Images==== | ||
<gallery> | <gallery> | ||
Image:Breast_fibroadenoma_by_fine_needle_aspiration_%282%29_PAP_stain.jpg | Fibroadenoma - FNA (WC) | Image:Breast_fibroadenoma_by_fine_needle_aspiration_%282%29_PAP_stain.jpg | Fibroadenoma - FNA (WC) | ||
Image:Breast_fibroadenoma_by_fine_needle_aspiration_%281%29_DG_stain.jpg | Fibroadenoma FNA - Diff-Quik (WC) | Image:Breast_fibroadenoma_by_fine_needle_aspiration_%281%29_DG_stain.jpg | Fibroadenoma FNA - Diff-Quik (WC) | ||
</gallery> | </gallery> | ||
www: | |||
*[http://www.flickr.com/photos/jian-hua_qiao_md/3975095095/ Fibroadenoma (flickr.com)]. | |||
==Apocrine metaplasia/fibrocystic changes== | ==Apocrine metaplasia/fibrocystic changes== | ||
| Line 194: | Line 196: | ||
**Vacuolated cytoplasm + round/oval nuclei. | **Vacuolated cytoplasm + round/oval nuclei. | ||
Image | ====Image==== | ||
<gallery> | |||
Image:Fibrocystic_changes_of_breast_-_cytology_1.jpg | Oncocytes in FCC. (WC) | |||
</gallery> | |||
==Paget's disease== | ==Paget's disease== | ||
| Line 219: | Line 223: | ||
*Fibroadenoma - has single cells without cytoplasm. | *Fibroadenoma - has single cells without cytoplasm. | ||
Image | ====Image==== | ||
<gallery> | <gallery> | ||
Image:Breast_papillary_neoplasm_1.jpg | Papillary neoplasm. (WC) | Image:Breast_papillary_neoplasm_1.jpg | Papillary neoplasm. (WC) | ||