Difference between revisions of "Bizarre parosteal osteochondromatous proliferation"
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Image:[[File:Bone BizzareParostealOsteochondromatousProliferation PA (2).JPG|thumb|Notice the disorganized blue tinted cartilage with partial ossification merging into mature bone.]] | |||
Image:[[File:Bone BizzareParostealOsteochondromatousProliferation PA.JPG|thumb|A loose proliferation of fibroblasts fills the spaces between the bony trabeculae.]] | |||
*BPOP[http://www.webpathology.com/images/noimage.gif] | *BPOP[http://www.webpathology.com/images/noimage.gif] | ||
*BPOP[http://webpathology.com/images/noimage.gif] | *BPOP[http://webpathology.com/images/noimage.gif] | ||
Revision as of 06:58, 17 October 2014
| Bizarre parosteal osteochondromatous proliferation | |
|---|---|
| Diagnosis in short | |
|
| |
| Synonyms | Nora lesion |
| Site | Hands, feet |
|
| |
General
A distinctive osteochondromatous proliferation of hands and feet.
Population
- Young adults
- 20s-30s
Location
Hands and feet
Radiology
Marginated wide based bony growth projecting into the soft tissues[1]
Gross
- Nodule covered with glistening cartilage
Microscopic
Disorganized cellular cartilage with a blue tint and patchy ossification matures into disorganized bone. A proliferation of fibroblasts surrounds the lesion and occupies intertrabecular spaces.
Images
Image:
.JPG)
Image:
![[1]](http://www.webpathology.com/images/noimage.gif){kind=link}
![[2]](http://webpathology.com/images/noimage.gif){kind=link}
![[4]](http://pathologyoutlines.com/wick/bizarre%20parosteal%20osteochondromatous%20proliferation%20(bpop-%20no.jpg){kind=link}
DDX
- Periosteal chondrosarcoma
- Periosteal chondroma
- Low grade parosteal osteosarcoma
- Osteochondroma
Diangostic categories
- Cartilaginous neoplasms
- Osteocartilaginous neoplasms
Molecular
t(1:17)(q32;q21)[2]
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- BIZARRE PAROSTEAL OSTEOCHONDROMATOUS PROLIFERATION (NORA LESION).
- APPROPRIATE MARGIN STATEMENT.
Prognosis
- Benign
- Locally aggressive
See also
- Pathology Outlines[5]
References
- ↑ http://radiopaedia.org/articles/bizarre-parosteal-osteochondromatous-proliferation
- ↑ Kuruvilla, S.; Marco, R.; Raymond, AK.; Al-Ibraheemi, A.; Tatevian, N. (2011). "BizarreParosteal Osteochondromatous Proliferation (Nora's lesion) with translocation t(1;17)(q32;q21): a case report and role of cytogenetic studies on diagnosis.". Ann Clin Lab Sci 41 (3): 285-7. PMID 22075515.