Difference between revisions of "Bizarre parosteal osteochondromatous proliferation"

From Libre Pathology
Jump to navigation Jump to search
Line 66: Line 66:
*Osteocartilaginous neoplasms
*Osteocartilaginous neoplasms


==Stains==
==IHC==
==Molecular==
==Molecular==
t(1:17)(q32;q21)<ref>{{Cite journal  | last1 = Kuruvilla | first1 = S. | last2 = Marco | first2 = R. | last3 = Raymond | first3 = AK. | last4 = Al-Ibraheemi | first4 = A. | last5 = Tatevian | first5 = N. | title = BizarreParosteal Osteochondromatous Proliferation (Nora's lesion) with translocation t(1;17)(q32;q21): a case report and role of cytogenetic studies on diagnosis. | journal = Ann Clin Lab Sci | volume = 41 | issue = 3 | pages = 285-7 | month =  | year = 2011 | doi =  | PMID = 22075515 }}
t(1:17)(q32;q21)<ref>{{Cite journal  | last1 = Kuruvilla | first1 = S. | last2 = Marco | first2 = R. | last3 = Raymond | first3 = AK. | last4 = Al-Ibraheemi | first4 = A. | last5 = Tatevian | first5 = N. | title = BizarreParosteal Osteochondromatous Proliferation (Nora's lesion) with translocation t(1;17)(q32;q21): a case report and role of cytogenetic studies on diagnosis. | journal = Ann Clin Lab Sci | volume = 41 | issue = 3 | pages = 285-7 | month =  | year = 2011 | doi =  | PMID = 22075515 }}
Line 73: Line 71:


==Sign out==
==Sign out==
BIZARRE PAROSTEAL OSTEOCHONDROMATOUS PROLIFERATION (NORA LESION).
==Prognosis==
==Prognosis==
*Benign
*Benign
Line 80: Line 80:
*Pathology Outlines[http://www.pathologyoutlines.com/topic/bonebizarreparosteal.html]
*Pathology Outlines[http://www.pathologyoutlines.com/topic/bonebizarreparosteal.html]


==References==
{{Reflist|1}}
==Introduction==
==Specimen opening==
==Protocol==
===Protocol notes===
===Alternate approaches===
==See also==
===Related protocols===
==References==
==References==
{{Reflist|1}}
{{Reflist|1}}

Revision as of 11:53, 16 October 2014

Bizarre parosteal osteochondromatous proliferation
Diagnosis in short

Synonyms Nora lesion
Site Hands, feet


General

A distinctive osteochondromatous proliferation of hands and feet.

Population

  • Young adults
  • 20s-30s

Location

Hands and feet

Radiology

Marginated wide based bony growth projecting into the soft tissues[1]

Gross

  • Nodule covered with glistening cartilage

Microscopic

Disorganized cellular cartilage with a blue tint and patchy ossification matures into disorganized bone. A proliferation of fibroblasts surrounds the lesion and occupies intertrabecular spaces.

Images

DDX

  • Periosteal chondrosarcoma
  • Periosteal chondroma
  • Low grade parosteal osteosarcoma
  • Osteochondroma

Diangostic categories

  • Cartilaginous neoplasms
  • Osteocartilaginous neoplasms

Molecular

t(1:17)(q32;q21)[2]

Sign out

BIZARRE PAROSTEAL OSTEOCHONDROMATOUS PROLIFERATION (NORA LESION).

Prognosis

  • Benign
  • Locally aggressive

See also

  • Pathology Outlines[5]

References

  1. http://radiopaedia.org/articles/bizarre-parosteal-osteochondromatous-proliferation
  2. Kuruvilla, S.; Marco, R.; Raymond, AK.; Al-Ibraheemi, A.; Tatevian, N. (2011). "BizarreParosteal Osteochondromatous Proliferation (Nora's lesion) with translocation t(1;17)(q32;q21): a case report and role of cytogenetic studies on diagnosis.". Ann Clin Lab Sci 41 (3): 285-7. PMID 22075515.