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Difference between revisions of "Basics"
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→Cytologic features and malignancy: more
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In diagnostic pathology, most stuff falls into the ''neoplastic'' category. | In diagnostic pathology, most stuff falls into the ''neoplastic'' category. | ||
===Cytologic features | ===Features of malignancy=== | ||
It is said that | ====Cytologic features==== | ||
It is said that:<ref name=boerner>S. Boerner. 12 September 2011.</ref> | |||
#It is the nuclear abnormalities that make a cell malignant. | #It is the nuclear abnormalities that make a cell malignant. | ||
#The cytoplasm that gives one clues as to the cell of origin. | #The cytoplasm that gives one clues as to the cell of origin. | ||
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§ mitoses are seen in poorly differentiated tumour and regeneration. High mitotic rate in the context of unremarkable nuclear morphology is usually not malignant. | § mitoses are seen in poorly differentiated tumour and regeneration. High mitotic rate in the context of unremarkable nuclear morphology is usually not malignant. | ||
====Other features==== | |||
In the context of [[soft tissue lesions]], it is said that the two most important features of malignancy are: | |||
#[[Necrosis]]. | |||
#High vascularity. | |||
Notes: | |||
*Benign soft tissue lesions may have marked [[nuclear atypia]] and abundant mitotic activity. | |||
===Basic pathologic differential diagnosis of malignancy=== | ===Basic pathologic differential diagnosis of malignancy=== | ||