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Difference between revisions of "Basal cell carcinoma"
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Image:Basal_cell_carcinoma_fibroepitheliomatous_pattern_-_very_low_mag.jpg | Fibroepithelioma of Pinkus. (WC/Nephron) | Image:Basal_cell_carcinoma_fibroepitheliomatous_pattern_-_very_low_mag.jpg | Fibroepithelioma of Pinkus. (WC/Nephron) | ||
Image:SkinTumors-P6040209.JPG | Fibroepithelioma of Pinkus. (WC) | Image:SkinTumors-P6040209.JPG | Fibroepithelioma of Pinkus. (WC) | ||
Fiboepithelioma of Pinkus 10x 4.tif | Fiboepithelioma of Pinkus 10x 4.tif (MLA) | |||
Fiboepithelioma of Pinkus 10x 3.tif | Fiboepithelioma of Pinkus 10x 3.tif (MLA) | |||
Fiboepithelioma of Pinkus 10x 2.tif | Fiboepithelioma of Pinkus 10x 2.tif (MLA) | |||
Fiboepithelioma of Pinkus 10x.tif | Fiboepithelioma of Pinkus 10x.tif (MLA) | |||
Fibro of pinkus.tif | Fiboepithelioma of Pinkus 4x.tif (MLA) | |||
</gallery> | </gallery> | ||
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*[[Ber-EP4]] +ve -- typically weak and focal staining. | *[[Ber-EP4]] +ve -- typically weak and focal staining. | ||
**[[Microcystic adnexal carcinoma]] negative.<ref name=pmid23398472 >{{Cite journal | last1 = Sellheyer | first1 = K. | last2 = Nelson | first2 = P. | last3 = Kutzner | first3 = H. | last4 = Patel | first4 = RM. | title = The immunohistochemical differential diagnosis of microcystic adnexal carcinoma, desmoplastic trichoepithelioma and morpheaform basal cell carcinoma using BerEP4 and stem cell markers. | journal = J Cutan Pathol | volume = 40 | issue = 4 | pages = 363-70 | month = Apr | year = 2013 | doi = 10.1111/cup.12085 | PMID = 23398472 }}</ref> | **[[Microcystic adnexal carcinoma]] negative.<ref name=pmid23398472 >{{Cite journal | last1 = Sellheyer | first1 = K. | last2 = Nelson | first2 = P. | last3 = Kutzner | first3 = H. | last4 = Patel | first4 = RM. | title = The immunohistochemical differential diagnosis of microcystic adnexal carcinoma, desmoplastic trichoepithelioma and morpheaform basal cell carcinoma using BerEP4 and stem cell markers. | journal = J Cutan Pathol | volume = 40 | issue = 4 | pages = 363-70 | month = Apr | year = 2013 | doi = 10.1111/cup.12085 | PMID = 23398472 }}</ref> | ||
*CK5/6 +ve. | *CK5/6 +ve (52 of 52<ref name=pmid18496426/>). | ||
**Useful to assess [[margins]]... if very close. | **Useful to assess [[margins]]... if very close. | ||
*CK7 +ve (30 +ve of 52 cases<ref name=pmid18496426>{{cite journal |authors=Alessi E, Venegoni L, Fanoni D, Berti E |title=Cytokeratin profile in basal cell carcinoma |journal=Am J Dermatopathol |volume=30 |issue=3 |pages=249–55 |date=June 2008 |pmid=18496426 |doi=10.1097/DAD.0b013e31816c828a |url=}}</ref>). | |||
*CK19 -ve/+ve (14 +ve 52<ref name=pmid18496426/>). | |||
*CD10 +ve. | *CD10 +ve. | ||
*Actin +ve. | *Actin +ve. | ||
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===Electrodesiccation and curettage=== | ===Electrodesiccation and curettage=== | ||
<pre> | <pre> | ||
SKIN LESION, SHAVE BIOPSY WITH ELECTRODESICCATION AND CURETTAGE (EDC): | Skin, Left Brow, Biopsy with Electrodesiccation and Curettage (EDC): | ||
- BASAL CELL CARCINOMA, margin status assessed clinically during EDC. | |||
</pre> | |||
====Block letters==== | |||
<pre> | |||
SKIN LESION, LEFT FOREARM, SHAVE BIOPSY WITH ELECTRODESICCATION AND CURETTAGE (EDC): | |||
- BASAL CELL CARCINOMA, MARGIN STATUS ASSESSED CLINICALLY DURING EDC. | - BASAL CELL CARCINOMA, MARGIN STATUS ASSESSED CLINICALLY DURING EDC. | ||
- EXTENSIVE SOLAR ELASTOSIS. | - EXTENSIVE SOLAR ELASTOSIS. | ||