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| Caption = [[Micrograph]] showing atypical adenomatous hyperplasia. [[H&E stain]]. | | Caption = [[Micrograph]] showing atypical adenomatous hyperplasia. [[H&E stain]]. | ||
| Synonyms = atypical alveolar hyperplasia | | Synonyms = atypical alveolar hyperplasia | ||
| Micro = | | Micro = enlarged alveolar lining cells with [[hobnail morphology]], round or oval hyperchromatic nuclei; spaces are typically seen between the alveolar lining cells '''important'''; limited extent (must be <5 mm); +/-nuclear enlargement (mild-to-moderate), +/-multinucleation | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[adenocarcinoma in situ]] of lung, [[lung adenocarcinoma]], [[multifocal micronodular pneumocyte hyperplasia associated with tuberous sclerosis]] | | LMDDx = [[adenocarcinoma in situ]] of lung, [[lung adenocarcinoma]], [[multifocal micronodular pneumocyte hyperplasia associated with tuberous sclerosis]] | ||
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| Syndromes = | | Syndromes = | ||
| Clinicalhx = | | Clinicalhx = | ||
| Signs = | | Signs = | ||
| Symptoms = | | Symptoms = | ||
| Prevalence = | | Prevalence = relatively common | ||
| Bloodwork = | | Bloodwork = | ||
| Rads = | | Rads = ground glass opacity (persistent) | ||
| Endoscopy = | | Endoscopy = | ||
| Prognosis = benign, need to exclude [[lung adenocarcinoma]] | | Prognosis = benign, need to exclude [[lung adenocarcinoma]] | ||
| Other = | | Other = | ||
| ClinDDx = [[ | | ClinDDx = [[pneumonia]] (chronic), [[lung tumours]] | ||
| Tx = surgical excision | | Tx = surgical excision | ||
}} | }} | ||
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===Images=== | ===Images=== | ||
<gallery> | |||
Image: Atypical adenomatous hyperplasia -- low mag.jpg | AAH - low mag. (WC) | |||
Image: Atypical adenomatous hyperplasia -- intermed mag.jpg | AAH - intermed. mag. (WC) | |||
Image: Atypical adenomatous hyperplasia - alt -- high mag.jpg | AAH - high mag. (WC) | |||
Image: Atypical adenomatous hyperplasia -- very high mag.jpg | AAH - very high mag. (WC) | |||
</gallery> | |||
====www==== | |||
*[http://www.nature.com/modpathol/journal/v20/n9/fig_tab/3800929f1.html#figure-title AAH (nature.com)].<ref name=pmid17618248/> | *[http://www.nature.com/modpathol/journal/v20/n9/fig_tab/3800929f1.html#figure-title AAH (nature.com)].<ref name=pmid17618248/> | ||
*[http://www.jthoracdis.com/article/viewFile/1518/html/9359 AAH (jthoracdis.com)].<ref>{{Cite journal | last1 = Davidson | first1 = MR. | last2 = Gazdar | first2 = AF. | last3 = Clarke | first3 = BE. | title = The pivotal role of pathology in the management of lung cancer. | journal = J Thorac Dis | volume = 5 | issue = Suppl 5 | pages = S463-S478 | month = Oct | year = 2013 | doi = 10.3978/j.issn.2072-1439.2013.08.43 | PMID = 24163740 }}</ref> | *[http://www.jthoracdis.com/article/viewFile/1518/html/9359 AAH (jthoracdis.com)].<ref>{{Cite journal | last1 = Davidson | first1 = MR. | last2 = Gazdar | first2 = AF. | last3 = Clarke | first3 = BE. | title = The pivotal role of pathology in the management of lung cancer. | journal = J Thorac Dis | volume = 5 | issue = Suppl 5 | pages = S463-S478 | month = Oct | year = 2013 | doi = 10.3978/j.issn.2072-1439.2013.08.43 | PMID = 24163740 }}</ref> |
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