48,448
edits
Difference between revisions of "Anus"
Jump to navigation
Jump to search
→Perianal abscess: +fistula
(→Perianal abscess: +fistula) |
|||
| Line 38: | Line 38: | ||
====Micro==== | ====Micro==== | ||
The sections show skin with acanthosis, hypergranulosis, compact hyperkeratosis and focal full thickness loss of the epidermis, associated with a mixed inflammatory infiltrate. The dermis has reactive fibroblasts with moderate grey cytoplasm, nuclear enlargement and round small nucleoli. The fibroblast nuclei have regular nuclear membranes and a bland chromatin pattern. Clusters of neutrophils are present. There is no epidermal nuclear atypia. Mitotic activity is seen focally. No atypical mitotic figures are apparent. The inflammation extends to the deep aspect of the specimen. | The sections show skin with acanthosis, hypergranulosis, compact hyperkeratosis and focal full thickness loss of the epidermis, associated with a mixed inflammatory infiltrate. The dermis has reactive fibroblasts with moderate grey cytoplasm, nuclear enlargement and round small nucleoli. The fibroblast nuclei have regular nuclear membranes and a bland chromatin pattern. Clusters of neutrophils are present. There is no epidermal nuclear atypia. Mitotic activity is seen focally. No atypical mitotic figures are apparent. The inflammation extends to the deep aspect of the specimen. | ||
==Anal fistula== | |||
===General=== | |||
*[[Clinical diagnosis]]. | |||
*May be seen in association with an [[perianal abscess|abscess]]. | |||
*Common in Crohn's disease.<ref name=pmid23798025>{{Cite journal | last1 = Burri | first1 = E. | last2 = Vavricka | first2 = SR. | title = [Perianal Crohn's disease]. | journal = Ther Umsch | volume = 70 | issue = 7 | pages = 417-28 | month = Jul | year = 2013 | doi = 10.1024/0040-5930/a000427 | PMID = 23798025 }}</ref> | |||
===Microscopic=== | |||
Features: | |||
*Squamous mucosa with acute and chronic inflammation. | |||
DDx: | |||
*[[Squamous cell carcinoma]].<ref name=pmid23069004>{{Cite journal | last1 = Benjelloun | first1 = el B. | last2 = Abkari | first2 = M. | last3 = Ousadden | first3 = A. | last4 = Ait Taleb | first4 = K. | title = Squamous cell carcinoma associated anal fistulas in Crohn's disease unique case report with literature review. | journal = J Crohns Colitis | volume = 7 | issue = 6 | pages = e232-5 | month = Jul | year = 2013 | doi = 10.1016/j.crohns.2012.09.015 | PMID = 23069004 }}</ref> | |||
==Hidradenoma papilliferum== | ==Hidradenoma papilliferum== | ||