Angioinvasion

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Angioinvasion, also vascular invasion, is spread of tumour into a blood vessel.[1]

Angioinvasion is typically lumped with lymphatic invasion and referred to as lymphovascular invasion. This article only deals with angioinvasion.

General

The distinction between lymphatic invasion and lymphovascular invasion is usually not important. One important exception is the thyroid gland.[2]

Microscopic

Features:

  • Tumour within a vascular space.
    • Vascular space: endothelial cells, red blood cells.

Note:

  • One strict definitions requires thrombus adherent to tumour.[2]

DDx:

See also

References

  1. URL: https://www.tititudorancea.net/z/angioinvasion.htm. Accessed on: 24 November 2016.
  2. 2.0 2.1 Mete, O.; Asa, SL. (Dec 2011). "Pathological definition and clinical significance of vascular invasion in thyroid carcinomas of follicular epithelial derivation.". Mod Pathol 24 (12): 1545-52. doi:10.1038/modpathol.2011.119. PMID 21804527.