48,466
edits
Difference between revisions of "An introduction to head and neck pathology"
Jump to navigation
Jump to search
An introduction to head and neck pathology (view source)
Revision as of 17:37, 4 March 2022
, 17:37, 4 March 2022→Anatomy
| (12 intermediate revisions by the same user not shown) | |||
| Line 4: | Line 4: | ||
Cytopathology of the head and neck is dealt with in a separate article called ''[[head and neck cytopathology]]''. | Cytopathology of the head and neck is dealt with in a separate article called ''[[head and neck cytopathology]]''. | ||
=Anatomy= | |||
[[Image:Blausen_0872_UpperRespiratorySystem.png|thumb|Head and neck anatomy (BruceBlaus/WC).]] | |||
*Oropharynx - includes: tonsil, tonsillar pillar, base of tongue, soft palate.<ref>URL: [https://www.cancer.org/cancer/oral-cavity-and-oropharyngeal-cancer/about/what-is-oral-cavity-cancer.html https://www.cancer.org/cancer/oral-cavity-and-oropharyngeal-cancer/about/what-is-oral-cavity-cancer.html]. Accessed on: 1 April 2021.</ref><ref>URL: [http://www.headandneckcancerguide.org/teens/cancer-basics/explore-cancer-types/throat-cancer/oropharyngeal-cancer/soft-palate-cancer/ http://www.headandneckcancerguide.org/teens/cancer-basics/explore-cancer-types/throat-cancer/oropharyngeal-cancer/soft-palate-cancer/]. Accessed on: 15 November 2016.</ref> | |||
*Oral cavity - includes floor of mouth, bucca, anterior 2/3 of tongue,<ref>URL: [http://www.headandneckcancerguide.org/teens/cancer-basics/explore-cancer-types/oral-cancers/tongue-cancer/ http://www.headandneckcancerguide.org/teens/cancer-basics/explore-cancer-types/oral-cancers/tongue-cancer/]. Accessed on: 15 November 2016.</ref> lips, [[hard palate]], upper & lower alveolar ridge, retromolar trigone.<ref>URL: [http://www.headandneckcancerguide.org/teens/cancer-basics/explore-cancer-types/oral-cancers/oromandibular-cancer/ http://www.headandneckcancerguide.org/teens/cancer-basics/explore-cancer-types/oral-cancers/oromandibular-cancer/]. Accessed on: 15 November 2016.</ref> | |||
*Laryngopharynx. | |||
*Nasopharynx. | |||
=Clinical= | =Clinical= | ||
Common lesions:<ref name=Ref_PBoD780>{{Ref PBoD|780}}</ref> | Common lesions:<ref name=Ref_PBoD780>{{Ref PBoD|780}}</ref> | ||
*Leukoplakia. | *[[Leukoplakia]]. | ||
**Homogeneous. | **Homogeneous. | ||
**Non-homogeneous. | **Non-homogeneous. | ||
| Line 19: | Line 26: | ||
==Erythroplakia== | ==Erythroplakia== | ||
===General=== | ===General=== | ||
*Non-specific clinical finding - may be benign or malignant. | *Non-specific clinical finding - may be benign or [[malignant]]. | ||
*Strong association with non-keratinizing squamous lesions (invasive and dysplastic). | *Strong association with non-keratinizing squamous lesions (invasive and dysplastic). | ||
| Line 149: | Line 156: | ||
Work-up of negative H&E Bx differs by site: | Work-up of negative H&E Bx differs by site: | ||
* | *One large hospital: | ||
** | **LMWK (CAM5.2). | ||
** | **Pankeratin ([[AE1/AE3]]). | ||
* | *Another large hospital: | ||
**Nothing. | **Nothing. | ||
| Line 212: | Line 219: | ||
*[[AKA]] ''juvenile nasopharyngeal angiofibroma''. | *[[AKA]] ''juvenile nasopharyngeal angiofibroma''. | ||
{{Main|Nasopharyngeal angiofibroma}} | {{Main|Nasopharyngeal angiofibroma}} | ||
==Biphenotypic sinonasal sarcoma== | |||
*[[AKA]] ''low grade sinonasal sarcoma with neural and myogenic features''. | |||
{{Main|Biphenotypic sinonasal sarcoma}} | |||
=Nasal polyps= | =Nasal polyps= | ||