Difference between revisions of "An introduction to head and neck pathology"

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An introduction to head and neck pathology (view source)

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==Branchial cleft cyst==
==Branchial cleft cyst==
*[[AKA]] ''branchial cleft remnant''.
*[[AKA]] ''branchial cleft remnant''.
===General===
{{Main|Branchial cleft cyst}}
*Benign congenital thingy in the lateral neck.<ref>URL: [http://www.childrenshospital.org/az/Site663/mainpageS663P0.html http://www.childrenshospital.org/az/Site663/mainpageS663P0.html]. Accessed on: 15 March 2011.</ref>
*Most common cystic neck lesion in young adults.<ref name=pmid19593684>{{Cite journal  | last1 = Pietarinen-Runtti | first1 = P. | last2 = Apajalahti | first2 = S. | last3 = Robinson | first3 = S. | last4 = Passador-Santos | first4 = F. | last5 = Leivo | first5 = I. | last6 = Mäkitie | first6 = AA. | title = Cystic neck lesions: clinical, radiological and differential diagnostic considerations. | journal = Acta Otolaryngol | volume = 130 | issue = 2 | pages = 300-4 | month = Feb | year = 2010 | doi = 10.3109/00016480903127450 | PMID = 19593684 }}</ref>
*Treatment: excision.
 
===Gross===
*Lateral neck mass.
 
Image - clinical:
*[http://medical-dictionary.thefreedictionary.com/_/viewer.aspx?path=mosby&name=500051-fx23.jpg Branchial cleft cyst (thefreedictionary.com)].
 
===Microscopic===
Features:
*Cystic space lined by squamous epithelium - usually.
**+/-Inflammation.
*Connective tissue:
**+/-Adipose tissue.
**+/-Cartilage.
**+/-Bone.
**+/-Muscle.
 
DDx:
*Cystic [[squamous cell carcinoma]] - may be deceptively benign appearing.<ref name=pmid19593684>{{Cite journal  | last1 = Pietarinen-Runtti | first1 = P. | last2 = Apajalahti | first2 = S. | last3 = Robinson | first3 = S. | last4 = Passador-Santos | first4 = F. | last5 = Leivo | first5 = I. | last6 = Mäkitie | first6 = AA. | title = Cystic neck lesions: clinical, radiological and differential diagnostic considerations. | journal = Acta Otolaryngol | volume = 130 | issue = 2 | pages = 300-4 | month = Feb | year = 2010 | doi = 10.3109/00016480903127450 | PMID = 19593684 }}</ref>
 
====Images====
*[http://www.flickr.com/photos/jian-hua_qiao_md/8599213842/in/photostream/ BCC (flickr.com/Qiao)].
*[http://www.flickr.com/photos/jian-hua_qiao_md/8599214250/in/photostream/ BCC (flickr.com/Qiao)].
 
===IHC===
*p16 -ve.
**May be done to exclude a [[HPV-associated head and neck squamous cell carcinoma]].
*Ki-67 low.


==Benign lymphoepithelial lesion==
==Benign lymphoepithelial lesion==
Michael
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