Difference between revisions of "An introduction to gastrointestinal pathology"
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==Normal== | ==Normal== | ||
Layers of the alimentary canal:<ref>[http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Oral/Oral.htm]</ref><ref>[http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Oral/Images/gitplan.gif]</ref> | Layers of the alimentary canal:<ref>[http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Oral/Oral.htm]</ref><ref>[http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Oral/Images/gitplan.gif]</ref> | ||
* | *Mucosa (epithelium, lamina propria, muscularis mucosa). | ||
* | *Submuscosa and submucosal plexus (or Meissner's plexus). | ||
* | *Muscularis externa (inner longitudinal, myenteric plexus (or Auerbach's plexus) outer circumferential). | ||
* | *Adventitia (if retroperitoneal), serosa (if intraperitoneal). | ||
===Bowel=== | ===Bowel=== | ||
[[Small bowel]] | [[Small bowel]]: | ||
*Villi - should see three good ones in a normal biopsy. | *Villi - should see three good ones in a normal biopsy. | ||
*Crypts. | *Crypts. | ||
*Paneth cells. | *Paneth cells. | ||
[[Duodenum]] | [[Duodenum]]: | ||
*Small bowel (as above). | *Small bowel (as above). | ||
*Submucosal glands (Brunner's glands). | *Submucosal glands (Brunner's glands). | ||
Large bowel vs. small bowel | Large bowel vs. small bowel: | ||
*Small intestine. | *Small intestine. | ||
**Villi (key feature). | **Villi (key feature). | ||
| Line 42: | Line 42: | ||
==Small bowel== | ==Small bowel== | ||
{{main|Small bowel}} | {{main|Small bowel}} | ||
The part of the GI tract pathology mostly forgot. | The part of the GI tract that pathology has mostly forgot. | ||
===Duodenum=== | ===Duodenum=== | ||
{{main|Duodenum}} | {{main|Duodenum}} | ||
Commonly biopsied. | Commonly biopsied. Celiac... cancer... giardia? | ||
==Gallbladder== | ==Gallbladder== | ||
| Line 58: | Line 58: | ||
==Colon== | ==Colon== | ||
{{main|Colon}} | {{main|Colon}} | ||
Includes discussion of the [[rectum]]. | Includes discussion of the [[rectum]] and IBD. | ||
==Appendix== | ==Appendix== | ||
| Line 65: | Line 65: | ||
==See also== | ==See also== | ||
*[[Introduction]] | *[[Introduction]]. | ||
==References== | ==References== | ||
Revision as of 19:33, 13 May 2010
Gastrointestinal pathology is a large part of pathology as radiologists can often describe the extent of disease... but don't get the diagnosis right all the time.
Normal
Layers of the alimentary canal:[1][2]
- Mucosa (epithelium, lamina propria, muscularis mucosa).
- Submuscosa and submucosal plexus (or Meissner's plexus).
- Muscularis externa (inner longitudinal, myenteric plexus (or Auerbach's plexus) outer circumferential).
- Adventitia (if retroperitoneal), serosa (if intraperitoneal).
Bowel
- Villi - should see three good ones in a normal biopsy.
- Crypts.
- Paneth cells.
- Small bowel (as above).
- Submucosal glands (Brunner's glands).
Large bowel vs. small bowel:
- Small intestine.
- Villi (key feature).
- Brunner's glands - duodenum only (key feature).
- Paneth cells more common.
- Paneth cells are in the base of the crypts and have eosinophilic granules. They are found (normally) in the small bowel and right colon. They may appear on the left side (i.e. descending colon) in pathologic states, e.g. IBD.
- Large intestine
- More goblet cells.
- More lymphocytes usually.
Intestinal polyps
Main article: intestinal polyps
The bread and butter of gastrointestinal pathology.
Esophagus
Main article: Esophagus
Largely forgotten organ at SB... but no shortage of these at SMH.
Stomach
Main article: Stomach
H. pylori, cancer and more...
Small bowel
Main article: Small bowel
The part of the GI tract that pathology has mostly forgot.
Duodenum
Main article: Duodenum
Commonly biopsied. Celiac... cancer... giardia?
Gallbladder
Main article: Gallbladder
A growth industry... with the expanding waist lines in the (Western) world.
Liver
Main article: Liver
An organ that pathologists now sometimes forget.
Colon
Main article: Colon
Includes discussion of the rectum and IBD.
Appendix
Main article: Appendix
Acute appendicitis and more...
![[2]](http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Oral/Images/gitplan.gif){kind=link}