Difference between revisions of "An introduction to gastrointestinal pathology"

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(→‎Accessory GI: +pancreas)
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==Normal==
==Normal==
===Layers===
Layers of the alimentary canal:<ref>URL: [http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Oral/Oral.htm http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Oral/Oral.htm].</ref><ref>URL: [http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Oral/Images/gitplan.gif http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Oral/Images/gitplan.gif].</ref>
Layers of the alimentary canal:<ref>URL: [http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Oral/Oral.htm http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Oral/Oral.htm].</ref><ref>URL: [http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Oral/Images/gitplan.gif http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Oral/Images/gitplan.gif].</ref>
*Mucosa (epithelium, lamina propria, muscularis mucosa).
*Mucosa (epithelium, lamina propria, muscularis mucosa).
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*Muscularis externa (inner longitudinal, myenteric plexus (or Auerbach's plexus) outer circumferential).
*Muscularis externa (inner longitudinal, myenteric plexus (or Auerbach's plexus) outer circumferential).
*Adventitia (if retroperitoneal), serosa (if intraperitoneal).
*Adventitia (if retroperitoneal), serosa (if intraperitoneal).
===Cell types===
*Goblet cells.
**Secrete mucin.
*Enterochromaffin cells, [[AKA]] Kulchitsky cells.
**Subnuclear eosinophilic granules.
***Serotonin.
*Paneth cells.
**Supranuclear eosinophilic granules.
Memory device:
*Su'''p'''ranuclear granules = '''p'''aneth cell.


===Bowel===
===Bowel===
[[Small bowel]]:
====[[Small bowel]]====
*Villi - should see three good ones in a normal biopsy.
*Villi - should see three good ones in a normal biopsy.
*Crypts.
*Crypts.
*Paneth cells.
*Paneth cells.
*Goblet cells.
**Few in proximal small bowel (duodenum).
**Abundant in distal small bowel (ileum).


[[Duodenum]]:
====[[Duodenum]]====
*Small bowel (as above).
*Small bowel (as above).
*Submucosal glands (Brunner's glands).
*Submucosal glands (Brunner's glands).


Large bowel vs. small bowel:
====Large bowel vs. small bowel====
*Small intestine.
*Small intestine.
**Villi (key feature).
**Villi (key feature).
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