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Difference between revisions of "Amyloid"
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→Abdomen
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===General=== | ===General=== | ||
*Abdominal fat pad biopsy - common screen for amyloidosis. | *Abdominal fat pad biopsy - common screen for amyloidosis. | ||
**May be done with FNA. | |||
***Suffers for poor sensitivity.<ref name=pmid21760829>{{Cite journal | last1 = Devata | first1 = S. | last2 = Hari | first2 = P. | last3 = Markelova | first3 = N. | last4 = Li | first4 = R. | last5 = Komorowski | first5 = R. | last6 = Shidham | first6 = VB. | title = Detection of amyloid in abdominal fat pad aspirates in early amyloidosis: Role of electron microscopy and Congo red stained cell block sections. | journal = Cytojournal | volume = 8 | issue = | pages = 11 | month = | year = 2011 | doi = 10.4103/1742-6413.82278 | PMID = 21760829 }}</ref> | |||
===Microscopic=== | ===Microscopic=== | ||
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*Small-to-intermediate sized arteries with a thickened amorphous eosinophilic media. | *Small-to-intermediate sized arteries with a thickened amorphous eosinophilic media. | ||
**Thickening classically nodular. | **Thickening classically nodular. | ||
**Apple green-birefringence -- with polarization. | |||
Note: | |||
*Evaluation of at least 15 small blood vessels is recommended.<ref name=pmid21760829/> | |||
===Stains=== | ===Stains=== | ||
*Congo red +ve. | *[[Congo red]] +ve. | ||
**Orange/light red = positive. | |||
===Sign out=== | ===Sign out=== | ||