Difference between revisions of "Amnion nodosum"

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'''Amnion nodosum''' is an uncommon benign [[placental pathology]].
'''Amnion nodosum''' is an uncommon benign [[placental pathology]].


===General===
==General==
*Associated with (long-standing) [[oligohydramnios]].<ref>URL: [http://library.med.utah.edu/WebPath/PLACHTML/PLAC042.html http://library.med.utah.edu/WebPath/PLACHTML/PLAC042.html]. Accessed on: 12 January 2011.</ref>
*Associated with (long-standing) [[oligohydramnios]].<ref>URL: [http://library.med.utah.edu/WebPath/PLACHTML/PLAC042.html http://library.med.utah.edu/WebPath/PLACHTML/PLAC042.html]. Accessed on: 12 January 2011.</ref>
*Should be separated from ''squamous metaplasia of amnion''.
*Should be separated from ''squamous metaplasia of amnion''.


===Gross===
==Gross==
Features:<ref name=pmid18081444>{{Cite journal  | last1 = Adeniran | first1 = AJ. | last2 = Stanek | first2 = J. | title = Amnion nodosum revisited: clinicopathologic and placental correlations. | journal = Arch Pathol Lab Med | volume = 131 | issue = 12 | pages = 1829-33 | month = Dec | year = 2007 | doi = 10.1043/1543-2165(2007)131[1829:ANRCAP]2.0.CO;2 | PMID = 18081444 }}</ref>
Features:<ref name=pmid18081444>{{Cite journal  | last1 = Adeniran | first1 = AJ. | last2 = Stanek | first2 = J. | title = Amnion nodosum revisited: clinicopathologic and placental correlations. | journal = Arch Pathol Lab Med | volume = 131 | issue = 12 | pages = 1829-33 | month = Dec | year = 2007 | doi = 10.1043/1543-2165(2007)131[1829:ANRCAP]2.0.CO;2 | PMID = 18081444 }}</ref>
*Yellow nodules ~ 1-5 mm.
*Yellow nodules ~ 1-5 mm.
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*[[Squamous metaplasia of the amnion]] - large irregular patches, usu. white.
*[[Squamous metaplasia of the amnion]] - large irregular patches, usu. white.


Images:
===Images===
*[http://www.webpathology.com/image.asp?n=2&Case=659 Amnion nodosum (webpathology.com)].
*[http://www.webpathology.com/image.asp?n=2&Case=659 Amnion nodosum (webpathology.com)].
*[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-131-12-1829-f01&doi=10.1043%2F1543-2165%282007%29131%5B1829%3AANRCAP%5D2.0.CO%3B2 Amnion nodosum & squamous metaplasia of the amnion (archivesofpathology.org)].<ref name=pmid18081444/>
*[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-131-12-1829-f01&doi=10.1043%2F1543-2165%282007%29131%5B1829%3AANRCAP%5D2.0.CO%3B2 Amnion nodosum & squamous metaplasia of the amnion (archivesofpathology.org)].<ref name=pmid18081444/>
<!-- annoying use of '[' and ']' - had to go find escape characters here: http://www.w3schools.com/tags/ref_urlencode.asp -->
<!-- annoying use of '[' and ']' - had to go find escape characters here: http://www.w3schools.com/tags/ref_urlencode.asp -->


===Microscopic===
==Microscopic==
Features:<ref name=pmid18081444/>
Features:<ref name=pmid18081444/>
*Stratified squamous epithelium - non-keratinizing ''or'' minimal keratin.
*Stratified squamous epithelium - non-keratinizing ''or'' minimal keratin.
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*Normal amnion = simple epithelium.
*Normal amnion = simple epithelium.


Images:
===Images===
*[http://www.webpathology.com/image.asp?case=659&n=3 Amnion nodosum (webpathology.com)].
*[http://www.webpathology.com/image.asp?case=659&n=3 Amnion nodosum (webpathology.com)].
*[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-131-12-1829-f01&doi=10.1043%2F1543-2165%282007%29131%5B1829%3AANRCAP%5D2.0.CO%3B2 Amnion nodosum & squamous metaplasia of the amnion (archivesofpathology.org)].<ref name=pmid18081444/>
*[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-131-12-1829-f01&doi=10.1043%2F1543-2165%282007%29131%5B1829%3AANRCAP%5D2.0.CO%3B2 Amnion nodosum & squamous metaplasia of the amnion (archivesofpathology.org)].<ref name=pmid18081444/>

Revision as of 15:22, 17 April 2016

Amnion nodosum is an uncommon benign placental pathology.

General

  • Associated with (long-standing) oligohydramnios.[1]
  • Should be separated from squamous metaplasia of amnion.

Gross

Features:[2]

  • Yellow nodules ~ 1-5 mm.
    • Some think they are white.[3]

DDx:

Images

Microscopic

Features:[2]

  • Stratified squamous epithelium - non-keratinizing or minimal keratin.
  • Amorphous acidophilic (pink) debris.

Note:

  • Normal amnion = simple epithelium.

Images

See also

References

  1. URL: http://library.med.utah.edu/WebPath/PLACHTML/PLAC042.html. Accessed on: 12 January 2011.
  2. 2.0 2.1 2.2 2.3 Adeniran, AJ.; Stanek, J. (Dec 2007). "Amnion nodosum revisited: clinicopathologic and placental correlations.". Arch Pathol Lab Med 131 (12): 1829-33. doi:10.1043/1543-2165(2007)131[1829:ANRCAP]2.0.CO;2. PMID 18081444.
  3. CS. 7 February 2011.