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Difference between revisions of "Adamantinoma"
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# | '''Adamantinoma''' is an uncommon benign [[bone tumour]]. It should '''not''' be confused with ''[[adenomatoid tumour]]''. | ||
==General== | |||
Features:<ref name=Ref_WMSP650>{{Ref WMSP|650}}</ref> | |||
*Rare: < 1% of bone tumours. | |||
*25-35 years old. | |||
*Benign, may be locally aggressive. | |||
*Cousin of [[ameloblastoma]]. (???) | |||
==Gross== | |||
*Tibia or fibula. | |||
===Radiology=== | |||
*Intracortical, radiolucent. | |||
==Microscopic== | |||
Features: | |||
*Biphasic tumour: | |||
*#Fibrous/spindle cell component. | |||
*#Epithelial component. | |||
DDx:<ref name=pathcon_adam>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970057-2 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970057-2]. Accessed on: 28 April 2011.</ref> | |||
*Vascular tumours ([[Epithelioid hemangioendothelioma]]). | |||
*[[Metastatic carcinoma]]. | |||
===Images=== | |||
<gallery> | |||
Image:Adamantinoma_-_intermed_mag.jpg | Adamantinoma - intermed. mag. (WC) | |||
</gallery> | |||
www: | |||
*[http://southbaypath.org/CaseImages/sb5260/AdamantinomaBiopsy3.jpg Adamantinoma (southbaypath.org)].<ref>URL: [http://southbaypath.org/CaseImages/sb5260/sb5260.htm http://southbaypath.org/CaseImages/sb5260/sb5260.htm]. Accessed on: 7 December 2010.</ref> | |||
==IHC== | |||
Features:<ref name=pathcon_adam/> | |||
*CK14 +ve (HMWK).<ref>URL: [http://www.nordiqc.org/Epitopes/Cytokeratins/cytokeratins.htm http://www.nordiqc.org/Epitopes/Cytokeratins/cytokeratins.htm]. Accessed on: 28 April 2011.</ref> | |||
*CK19 +ve (LMWK). | |||
*CK8/18 -ve (LMWK). | |||
==See also== | |||
*[[Chondro-osseous tumours]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Chondro-osseous tumours]] | |||