Difference between revisions of "Acute duodenitis"

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{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Acute duodenitis -- intermed mag.jpg
| Width      =
| Caption    = Acute duodenitis. [[H&E stain]].
| Synonyms  =
| Micro      = [[neutrophil]]s - "found without searching", [[eosinophil]]s - "found without searching", plasma cells (increased), intraepithelial lymphocytes
| Subtypes  =
| LMDDx      =
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = [[duodenum]]
| Assdx      = [[Helicobacter gastritis]]
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = uncommon
| Bloodwork  =
| Rads      =
| Endoscopy  = erythema
| Prognosis  = benign
| Other      =
| ClinDDx    =
| Tx        = dependent on underlying cause
}}
'''Acute duodenitis''', abbreviated '''AD''', is an acute inflammatory process of the [[duodenum]]. It is relatively uncommon.
'''Acute duodenitis''', abbreviated '''AD''', is an acute inflammatory process of the [[duodenum]]. It is relatively uncommon.


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Features:
Features:
*Intraepithelial lymphocytes.
*Intraepithelial lymphocytes.
*Neutrophils - "found without searching" - '''key feature'''.
*[[Neutrophil]]s - "found without searching" - '''key feature'''.
*Eosinophils - "found without searching" - '''key feature'''.
*[[Eosinophil]]s - "found without searching" - '''key feature'''.
*Plasma cells (increased).
*[[Plasma cell]]s (increased).


Notes:
Notes:
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**[[NSAID]]s not commonly assoc. with acute inflammation;<ref name=pmid8406146>{{cite journal |author=Taha AS, Dahill S, Nakshabendi I, Lee FD, Sturrock RD, Russell RI |title=Duodenal histology, ulceration, and Helicobacter pylori in the presence or absence of non-steroidal anti-inflammatory drugs |journal=Gut |volume=34 |issue=9 |pages=1162–6 |year=1993 |month=September |pmid=8406146 |pmc=1375446 |doi= |url=}}</ref> thus, without chronic inflammation NSAIDs are unlikely.
**[[NSAID]]s not commonly assoc. with acute inflammation;<ref name=pmid8406146>{{cite journal |author=Taha AS, Dahill S, Nakshabendi I, Lee FD, Sturrock RD, Russell RI |title=Duodenal histology, ulceration, and Helicobacter pylori in the presence or absence of non-steroidal anti-inflammatory drugs |journal=Gut |volume=34 |issue=9 |pages=1162–6 |year=1993 |month=September |pmid=8406146 |pmc=1375446 |doi= |url=}}</ref> thus, without chronic inflammation NSAIDs are unlikely.
***Acute NSAID-related duodenitis reported.<ref name=pmid18158085>{{cite journal |author=Hashash JG, Atweh LA, Saliba T, ''et al.'' |title=Acute NSAID-related transmural duodenitis and extensive duodenal ulceration |journal=Clin Ther |volume=29 |issue=11 |pages=2448–52 |year=2007 |month=November |pmid=18158085 |doi=10.1016/j.clinthera.2007.11.012 |url=}}</ref>
***Acute NSAID-related duodenitis reported.<ref name=pmid18158085>{{cite journal |author=Hashash JG, Atweh LA, Saliba T, ''et al.'' |title=Acute NSAID-related transmural duodenitis and extensive duodenal ulceration |journal=Clin Ther |volume=29 |issue=11 |pages=2448–52 |year=2007 |month=November |pmid=18158085 |doi=10.1016/j.clinthera.2007.11.012 |url=}}</ref>
===Images===
<gallery>
Image: Acute duodenitis -- low mag.jpg | AD - low mag.
Image: Acute duodenitis -- intermed mag.jpg | AD - intermed. mag.
Image: Acute duodenitis -- high mag.jpg | AD - high mag.
Image: Acute duodenitis -- very high mag.jpg | AD - very high mag.
</gallery>


==Sign out==
==Sign out==
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==See also==
==See also==
*[[Duodenum]].
*[[Duodenum]].
*[[Chronic duodenitis]].
*[[Crohn's disease]].


==References==
==References==
48,466

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