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Difference between revisions of "Actinic keratosis"
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→Histologic subtypes of actinic keratosis
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*Yellow-brown scaly, patches. | *Yellow-brown scaly, patches. | ||
*Sandpaper sensation - on touching. | *Sandpaper sensation - on touching. | ||
*Usually small (<1cm), but larger lesions may occur. | |||
*May be pigmented.<ref>URL: [http://www.dermoscopy-ids.org/index.php/newest-case/79-lentigo-maligna-vs-pigmented-actinic-keratosis http://www.dermoscopy-ids.org/index.php/newest-case/79-lentigo-maligna-vs-pigmented-actinic-keratosis]. Accessed on: 23 August 2012.</ref> | *May be pigmented.<ref>URL: [http://www.dermoscopy-ids.org/index.php/newest-case/79-lentigo-maligna-vs-pigmented-actinic-keratosis http://www.dermoscopy-ids.org/index.php/newest-case/79-lentigo-maligna-vs-pigmented-actinic-keratosis]. Accessed on: 23 August 2012.</ref> | ||
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*[[Seborrheic keratosis]] - should not have basilar nuclear atypia. | *[[Seborrheic keratosis]] - should not have basilar nuclear atypia. | ||
*[[Lichenoid keratosis]] (esp. for ''lichenoid actinic keratosis'') - has a band of inflammatory cells in the superficial dermis. | *[[Lichenoid keratosis]] (esp. for ''lichenoid actinic keratosis'') - has a band of inflammatory cells in the superficial dermis. | ||
*Discoid Luphus Erythematosus. | |||
===Images=== | ===Images=== | ||
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Image:SkinTumors-P5280065.JPG | Actinic keratosis. (WC) | Image:SkinTumors-P5280065.JPG | Actinic keratosis. (WC) | ||
Image:SkinTumors-P5280055.JPG | Actinic keartosis. (WC) | Image:SkinTumors-P5280055.JPG | Actinic keartosis. (WC) | ||
Image:SkinTumors-P5280056.JPG | Actinic keratosis. (WC) | |||
</gallery> | |||
<gallery> | |||
Image:Bowenoid_actinic_keratosis_-_high_mag.jpg | Bowenoid actinic keratosis - high mag. (WC) | Image:Bowenoid_actinic_keratosis_-_high_mag.jpg | Bowenoid actinic keratosis - high mag. (WC) | ||
Image:Bowenoid_actinic_keratosis_-_very_high_mag.jpg | Bowenoid actinic keratosis - very high mag. (WC) | Image:Bowenoid_actinic_keratosis_-_very_high_mag.jpg | Bowenoid actinic keratosis - very high mag. (WC) | ||
</gallery> | </gallery> | ||
===Histologic subtypes of actinic keratosis=== | ===Histologic subtypes of actinic keratosis=== | ||
Like most common things, there are several variants:<ref name=Ref_Derm353>{{Ref Derm|353}}</ref> | Like most common things, there are several variants:<ref name=Ref_Derm353>{{Ref Derm|353}}</ref> | ||
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*Lichenoid actinic keratosis - band of inflammatory cells at the dermal-epidermal junction. | *Lichenoid actinic keratosis - band of inflammatory cells at the dermal-epidermal junction. | ||
**DDx: [[lichen planus]]. | **DDx: [[lichen planus]]. | ||
*Atrophic actinic keratosis. | |||
==Sign out== | ==Sign out== | ||
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There is no clefting of the lesion from the surrounding stroma. Intercellular bridges are identified. | There is no clefting of the lesion from the surrounding stroma. Intercellular bridges are identified. | ||
=====Lichenoid AK===== | |||
The sections show skin with a lymphoplasmacytic interface dermatitis, hypergranulosis, hyperkeratosis, loss of the rete ridges and apoptotic keratinocytes. The epidermis matures to the surface; however, there is basal cell hyperplasia associated with moderate keratinocyte nuclear atypia (including hyperchromasia and anisonucleosis). Pigment incontinence is present. Solar elastosis is present. The lesion is completely excised in the plane of section. | |||
==See also== | ==See also== | ||