Intranodal palisaded myofibroblastoma

From Libre Pathology
Revision as of 03:09, 4 October 2011 by Michael (talk | contribs) (create)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

Intranodal palisaded myofibroblastoma, abbreviated IPM, is a rare tumour that classically presents as an inguinal mass.[1]

General

  • Rare.
  • Male:female = 2:1.
  • Adults - middle age.

Microscopic

Features:

  1. Rim of peripheral lymphoid tissue.
  2. spindle cells with nuclear palisading
  3. RBC extravasation/hemorrhage.
  4. Amianthoid fibers
  5. intracellular and extracellular fuchsinophilic bodies that stain positive for smooth muscle actin.

DDx:

Image:

IHC

  • SMA +ve.
  • Cyclin D1 +ve.

Other:

  • S100 -ve
  • GFAP -ve.
  • CD34 -ve.
  • Desmin -ve
  • Ki-67 - low.

See also

References

  1. ↑ Nguyen, T.; Eltorky, MA. (Feb 2007). "Intranodal palisaded myofibroblastoma.". Arch Pathol Lab Med 131 (2): 306-10. doi:10.1043/1543-2165(2007)131[306:IPM]2.0.CO;2. PMID 17284119.
Retrieved from "https://librepathology.org/w/index.php?title=Intranodal_palisaded_myofibroblastoma&oldid=8083"