BCL6
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BCL6 is a commonly used immunostain in hematopathology. BCL6 is gene and formally known as BCL6 transcription repressor.[1][2]
Normal staining
- Marks germinal centre cells.
Note:
- Usually paired with BCL2 which is normally negative in germinal centres.
Pathologic positive
- Diffuse large B-cell lymphoma - may be negative.
- Burkitt lymphoma.
- Others.
See also
- BCL2.
References
- ↑ URL: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001. Accessed on: April 26, 2022.
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 109565