SOX10
SOX10 is a common immunostain.
Positive
- Metastatic malignant melanoma 119 +ve of 125 cases.[1]
Salivary gland tumours:[2]
- Secretory carcinoma of the salivary gland.
- Sialoblastoma.
- Low-grade salivary duct carcinoma.
- Basal cell adenoma/basal cell adenocarcinoma.
- Mucoepidermoid carcinoma.
References
- ↑ Miettinen M, McCue PA, Sarlomo-Rikala M, Biernat W, Czapiewski P, Kopczynski J, Thompson LD, Lasota J, Wang Z, Fetsch JF (June 2015). "Sox10--a marker for not only schwannian and melanocytic neoplasms but also myoepithelial cell tumors of soft tissue: a systematic analysis of 5134 tumors". Am. J. Surg. Pathol. 39 (6): 826–35. doi:10.1097/PAS.0000000000000398. PMC 4431945. PMID 25724000. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431945/.
- ↑ "SOX10-positive salivary gland tumors: a growing list, including mammary analogue secretory carcinoma of the salivary gland, sialoblastoma, low-grade salivary duct carcinoma, basal cell adenoma/adenocarcinoma, and a subgroup of mucoepidermoid carcinoma". Hum Pathol 56: 134–42. October 2016. doi:10.1016/j.humpath.2016.05.021. PMID 27327192.