Atypical spindle cell lesions of the skin
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Atypical spindle cell lesions of the skin are uncommon but seen with enough frequency that one ought to be familiar with them.[1]
Spindle cell lesions of the skin directs here.
Classic
The differential diagnosis of atypical skin spindle cell lesions is SLAM:
- Spindle cell squamous cell carcinoma.
- Leiomyosarcoma.
- Atypical fibroxanthoma.
- Malignant melanoma.
Extended
DFSP. H&E stain.
A longer differential diagnosis that includes lesions with less atypia is SLAM DUNK:
- Spindle cell squamous cell carcinoma.
- Leiomyosarcoma.
- Angiosarcoma.
- Malignant melanoma.
- Dermatofibrosarcoma protuberans (DFSP).
- Undifferentiated pleomorphic sarcoma (AFX).
- Nodular fasciitis.
- Kaposi sarcoma.
See also
- ↑ Repertinger, S; Teruya, B; Sarma, D (2008). "Common Spindle Cell Malignant Neoplasms of the Skin: Differential Diagnosis and Review of the Literature". The Internet Journal of Dermatology 7 (2). http://ispub.com/IJD/7/2/11747.