Cancer antigen 125
Cancer antigen 125, abbreviated CA125 and CA-125, is a common immunostain and serum marker of disease. It is also known as mucin 16 and officially abbreviated MUC16.[1][2]
It is elevated in the serum in ovarian cancer and mildly or moderately elevated in endometriosis.
Positive
- Serous carcinoma.
- Breast carcinoma.
- Pancreatic ductal adenocarcinoma.[3]
- Epithelioid sarcoma - reported.[4]
See also
References
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 606154
- ↑ URL: http://www.ncbi.nlm.nih.gov/gene/94025. Accessed on: 3 August 2016.
- ↑ Jiang, K.; Tan, E.; Sayegh, Z.; Centeno, B.; Malafa, M.; Coppola, D. (Apr 2016). "Cancer Antigen 125 (CA125, MUC16) Protein Expression in the Diagnosis and Progression of Pancreatic Ductal Adenocarcinoma.". Appl Immunohistochem Mol Morphol. doi:10.1097/PAI.0000000000000368. PMID 27093451.
- ↑ Lee, HI.; Kang, KH.; Cho, YM.; Lee, OJ.; Ro, JY. (Jun 2006). "Proximal-type epithelioid sarcoma with elevated serum CA 125: report of a case with CA 125 immunoreactivity.". Arch Pathol Lab Med 130 (6): 871-4. doi:10.1043/1543-2165(2006)130[871:PESWES]2.0.CO;2. PMID 16740043.