Keratinising squamous metaplasia of the urinary bladder
Jump to navigation
Jump to search
Keratinising squamous metaplasia of the urinary bladder is a rare benign change of the urinary bladder associated with an increased risk of malignancy;[1] however, it is not considered a pre-malignant condition.[2]
General
- Non-keratinizing squamous metaplasia can be considered normal and is relatively common in trigone region of the bladder in women.
- Large age range (13-80 years).[1]
- Predominantly males - almost 4:1 (27 males:7 females in one series[1]).
Microscopic
Features:
- Squamous epithelium with hyperkeratosis or parakeratosis.
DDx:
- Squamous cell carcinoma of the urinary bladder.
- Metastatic squamous cell carcinoma, e.g. squamous cell carcinoma of the uterine cervix.
See also
References
- ↑ 1.0 1.1 1.2 Khan, MS.; Thornhill, JA.; Gaffney, E.; Loftus, B.; Butler, MR. (Nov 2002). "Keratinising squamous metaplasia of the bladder: natural history and rationalization of management based on review of 54 years experience.". Eur Urol 42 (5): 469-74. PMID 12429156.
- ↑ Kvist, E.; Sjølin, KE.; Laursen, H.; Orntoft, TF.; Sturmer, MA. (Jul 1992). "Squamous cell metaplasia of the bladder urothelium. A retrospective study of 36 patients.". APMIS 100 (7): 650-4. PMID 1379440.