Keratinising squamous metaplasia of the urinary bladder
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Keratinising squamous metaplasia of the urinary bladder is a rare benign change of the urinary bladder associated with an increased risk of malignancy.[1]
General
- Non-keratinizing squamous metaplasia can be considered normal and is relatively common in trigone region of the bladder in women.
- Large age range (13-80 years).[1]
- Predominantly males - almost 4:1 (27 males:7 females in one series[1]).
Microscopic
Features:
- Squamous epithelium with hyperkeratosis or parakeratosis.
DDx:
- Squamous cell carcinoma of the urinary bladder.
- Metastatic squamous cell carcinoma, e.g. squamous cell carcinoma of the uterine cervix.