Multifocal micronodular pneumocyte hyperplasia associated with tuberous sclerosis

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Multifocal micronodular pneumocyte hyperplasia associated with tuberous sclerosis, also multifocal micronodular pneumocyte hyperplasia in tuberous sclerosis, is the presence of rare hamartomatous lesions in the lung seen in tuberous sclerosis.[1]


General

  • Rare.

Microscopic

Features:

  • Macrophages within the air spaces.
  • Enlarged alveolar lining cells with:
    • Hobnail morphology - free (luminal) surface area > attached/basal surface area.
    • Round or oval nuclei.

DDx:

Images

  • MMPH - intermed. mag.

  • MMPH - high mag.

See also

References

  1. ↑ Nagar, AM.; Teh, HS.; Khoo, RN.; Morani, AC.; Vrishni, K.; Raghuram, J. (Feb 2008). "Multifocal pneumocyte hyperplasia in tuberous sclerosis.". Thorax 63 (2): 186. doi:10.1136/thx.2006.076604. PMID 18234663.
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