Pregnancy luteoma

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Pregnancy luteoma, also luteoma of pregnancy, is a rare benign ovarian tumour that arises in pregnancy.

General

  • Tumour of pregnancy.
  • Benign.
  • Regress after pregnancy; thus, conservative management.[1]

Clinical:

  • Increased serum testosterone.[2]
  • Increased CA125.[3][4]

Gross

  • Solid.
  • Yellow.

Images:

Microscopic

Features:

  • Sheets of cells.
  • Cells with eosinophilic cytoplasm, round nuclei and prominent nucleoli.

DDx:

Images

IHC

  • Inhibin +ve.[4]

See also

References

  1. Masarie, K.; Katz, V.; Balderston, K. (Sep 2010). "Pregnancy luteomas: clinical presentations and management strategies.". Obstet Gynecol Surv 65 (9): 575-82. doi:10.1097/OGX.0b013e3181f8c41d. PMID 21144088.
  2. Kao, HW.; Wu, CJ.; Chung, KT.; Wang, SR.; Chen, CY.. "MR imaging of pregnancy luteoma: a case report and correlation with the clinical features.". Korean J Radiol 6 (1): 44-6. PMID 15782020.
  3. Rodriguez, M.; Harrison, TA.; Nowacki, MR.; Saltzman, AK. (Nov 1999). "Luteoma of pregnancy presenting with massive ascites and markedly elevated CA 125.". Obstet Gynecol 94 (5 Pt 2): 854. PMID 10546765.
  4. 4.0 4.1 Wang, Y.; Zhou, F.; Qin, JL.; Qian, ZD.; Huang, LL. (2015). "Pregnancy luteoma followed with massive ascites and elevated CA125 after ovulation induction therapy: a case report and review of literatures.". Int J Clin Exp Med 8 (1): 1491-3. PMID 25785161.