Foveolar type dysplasia

Foveolar type dysplasia
Diagnosis in short
Foveolar dysplasia of the duodenum. H&E stain.
Synonyms	type 2 dysplasia, foveolar dysplasia, foveolar/hyperplastic dysplasia
LM DDx	benign foveolar epithelium, gastric heterotopia (if not stomach), benign ampullary epithelium, hyperplastic polyp
Site	stomach, duodenum (esp. ampulla of Vater), esophagus
Syndromes	familial adenomatous polyposis
Prevalence	not common
Other	may be subtle

Foveolar type dysplasia, also foveolar dysplasia, is a form of dysplasia that arises from the foveolar cells, typically seen in the stomach. It is may be subtle to unaccustomed eyes.

It is also described as non-adenomatous dysplasia, type 2 dysplasia and foveolar/hyperplastic type dysplasia.

General

• Precursor to adenocarcinoma.

Microscopic

Features:

• Tall columnar cells with basal nuclei in a villiform architecture.

DDx:

• Benign foveolar epithelium.
• Hyperplastic polyp.

Images

• 

  FD - intermed. mag.

• 

  FD - high mag.

www:

• Foveolar type dysplasia of the esophagus (nature.com).

See also

• Stomach.
• Gastric dysplasia.
• Ampulla of Vater.
• Esophageal dysplasia.