Clear cell carcinoma of the urinary bladder

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Clear cell carcinoma of the urinary bladder is a rare subtype of primary adenocarcinoma of the urinary bladder.

Clear cell carcinoma of the urinary bladder
Diagnosis in short
Synonyms mesonephroid adenocarcinoma, mesonephroid carcinoma
Subtypes subtype of primary adenocarcinoma of the urinary bladder
LM DDx nephrogenic adenoma, other subtypes of adenocarcinoma of the urinary bladder, urachal carcinoma
Site urinary bladder
Clinical history typically female
Prevalence very rare - case reports
Prognosis poor (?)

It is also known as mesonephroid adenocarcinoma of the urinary bladder, adenocarcinoma of bladder, mesonephroid type and mesonephroid carcinoma.

General

  • Extremely rare - 7 cases reported as of 2013.[1]
  • Female predominance (F:M ~ 2:1).[1]

Microscopic

Features:[1]

DDx:

IHC

  • CK7 +ve.
  • CD10 +ve.
  • CA-125 +ve.
  • GATA3 +ve.

Others:

  • ER -ve.
  • PR -ve.
  • CDX2 -ve.
  • AFP -ve.
  • PSA -ve.

See also

References

  1. ↑ 1.0 1.1 1.2 Abbas, M.; Kramer, MW.; Wolters, M.; Herrman, TR.; Becker, JU.; Kreipe, HH. (Feb 2013). "Adenocarcinoma of the urinary bladder, mesonephroid type: a rare case.". Rare Tumors 5 (1): e3. doi:10.4081/rt.2013.e3. PMID 23772302.
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