Dysembryoplastic neuroepithelial tumour
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'Dysembryoplastic neuroepithelial tumour, abbreviated DNT, is a rare neuropathology tumour that is associated with epilepsy.
General
Gross/radiology
- Temporal lobe.
- Variable architecture:[2] cystic, solitary nodular, multinodular.
Microscopic
Features:[2]
- Cells similar to oligodendrocytes:
- Large central nuclei with indentations.
- Multiple small nucleoli (common).
- Clear cytoplasm.
DDx:
- Oligodendroglioma.
- These have rounder, smaller nuclei with occasional nucleoli.[2]
Images
DNT (WC)
www:
See also
References
- ↑ Cataltepe, O.; Turanli, G.; Yalnizoglu, D.; Topçu, M.; Akalan, N. (Apr 2005). "Surgical management of temporal lobe tumor-related epilepsy in children.". J Neurosurg 102 (3 Suppl): 280-7. doi:10.3171/ped.2005.102.3.0280. PMID 15881751.
- ↑ 2.0 2.1 2.2 O'Brien, DF.; Farrell, M.; Delanty, N.; Traunecker, H.; Perrin, R.; Smyth, MD.; Park, TS. (Dec 2007). "The Children's Cancer and Leukaemia Group guidelines for the diagnosis and management of dysembryoplastic neuroepithelial tumours.". Br J Neurosurg 21 (6): 539-49. doi:10.1080/02688690701594817. PMID 18071981.