Myofibroma

From Libre Pathology
Revision as of 22:41, 15 November 2014 by Michael (talk | contribs)
Jump to navigation Jump to search

Myofibroma is a soft tissue lesion in the group fibroblastic/myofibroblastic tumours.

General

  • Benign.
  • Often < 2 years old; however, may be seen in adults.
  • Not common.[1]

Gross

  • Classically (oral) locations: tongue, buccal mucosa, lip.[1]

Microscopic

Features:[1]

  • Spindle cells with:
    • Tapering nuclei.
    • Eosinophilic cytoplasm.

Note:

DDx:

IHC

Features:[1]

  • Vimentin +ve.
  • SMA +ve.
  • S-100 -ve,

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 Brasileiro, BF.; Martins-Filho, PR.; Piva, MR.; da Silva, LC.; Nonaka, CF.; Miguel, MC. (Jul 2010). "Myofibroma of the oral cavity. A rare spindle cell neoplasm.". Med Oral Patol Oral Cir Bucal 15 (4): e596-600. PMID 20038894. http://www.medicinaoral.com/pubmed/medoralv15_i4_p596.pdf.
  2. ↑ Dray MS, McCarthy SW, Palmer AA, et al. (January 2006). "Myopericytoma: a unifying term for a spectrum of tumours that show overlapping features with myofibroma. A review of 14 cases". J. Clin. Pathol. 59 (1): 67–73. doi:10.1136/jcp.2005.028704. PMC 1860256. PMID 16394283. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860256/.
Retrieved from "https://librepathology.org/w/index.php?title=Myofibroma&oldid=34965"